Nectin-4 Specific LMW PET Probe Imaging in Urothelial Carcinoma

Inclusion Criteria:

1. 18-75 years old, male or female;

2. Heart function is normal;

3. Normal heart function;

4. Estimated survival ≥12 weeks;

5. Good follow-up compliance;

6. presence of at least one measurable target lesion according to RECIST1.1 criteria;

7. Women of childbearing age (15-49 years) must have a negative pregnancy test within 7days before starting the test; Fertile men and women must agree to use effectivecontraception to prevent pregnancy during the study period and for 3 months afterthe test;

8. Patients recommended by clinicians to undergo PET/CT examination for tumordiagnostic staging;

9. The subject patients could fully understand and voluntarily participate in theexperiment, and signed the informed consent.

Exclusion Criteria:

1. Serious abnormality of liver, kidney and blood;

2. Pregnant patients;

3. Pregnant and lactation women;

3. unable to lie flat for half an hour; 4) Refuse to join the clinical investigator; 5)Suffering from claustrophobia or other mental diseases; 6) Other conditions thatresearchers deem unsuitable for participating in the experiment.