The TEAM Long-Term Cohort Study (A Sub-study of TEAM(III))

Last updated: March 18, 2022
Sponsor: Australian and New Zealand Intensive Care Research Centre
Overall Status: Active - Enrolling

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT05298982
U1111-1195-3567-A9
  • Ages > 18
  • All Genders

Study Summary

This study is a prospective cohort study to evaluate the long-term effects of early activity and mobilisation compared to standard care on disability, function and health status for patients at 1, 2 and 5 years after recruitment of patients randomised into the TEAM Phase III RCT (ClinicalTrials.gov NCT03133377). The primary outcome of the study will be the level of disability as measured by the World Health Organisation's Disability Schedule 2.0, 12 level (WHODAS) at 2 years after recruitment.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Enrolled in the TEAM Phase III RCT Protocol.

Exclusion

Exclusion Criteria:

  • There are no exclusion criteria.

Study Design

Total Participants: 250
Study Start date:
February 11, 2020
Estimated Completion Date:
November 30, 2026

Study Description

Incomplete recovery following critical illness is a major public health problem in Australia.

Each year around 150,000 Australians are admitted to intensive care (ICU). These critically ill patients require substantial resources and invasive, expensive interventions. Approximately 10% die and many of the remaining patients who survive have delayed and compromised functional recovery. As many as 25% of the ICU survivors who were living at home prior to ICU are unable to return home due to impaired physical function. Globally, the quality of survival following an ICU admission has been identified as one of the largest health challenges for these patients. This study will address the quality of survival and long-term functional recovery for patients who require life support in ICU. These patients account for 62% of the total bed-days in Australian ICUs, with direct care costs of $2 billion per year. The long-term outcomes for these patients are very poor. In my Australian cohort study, 50% of patients who survived hospital had disability

Connect with a study center

  • Royal Prince Alfred Hospital

    Camperdown, New South Wales 2050
    Australia

    Site Not Available

  • John Hunter Hospital

    Sydney, New South Wales
    Australia

    Site Not Available

  • Royal North Shore Hospital

    Sydney, New South Wales
    Australia

    Site Not Available

  • Wollongong Hospital

    Wollongong, New South Wales
    Australia

    Site Not Available

  • Sunshine Coast University Hospital

    Birtinya, Queensland
    Australia

    Site Not Available

  • Mater Health

    Brisbane, Queensland
    Australia

    Site Not Available

  • Mater Private Hospital

    Brisbane, Queensland
    Australia

    Site Not Available

  • Caboolture Hospital

    Caboolture, Queensland
    Australia

    Site Not Available

  • Redcliffe Hospital

    Redcliffe, Queensland 4020
    Australia

    Site Not Available

  • Toowoomba Hospital

    Toowoomba, Queensland
    Australia

    Site Not Available

  • Launceston General Hospital

    Launceston, Tasmania
    Australia

    Site Not Available

  • Geelong Hospital - Barwon Health

    Geelong, Victoria 3220
    Australia

    Site Not Available

  • Cabrini Hospital

    Malvern, Victoria 3144
    Australia

    Site Not Available

  • Royal Melbourne Hospital

    Parkville, Victoria 3050
    Australia

    Site Not Available

  • Alfred Hospital

    Prahran, Victoria 3004
    Australia

    Site Not Available

  • Sunshine Hospital

    St Albans, Victoria 3021
    Australia

    Site Not Available

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.