Hypotension Prediction Index Based Perioperative Protocolized Hemodynamic Management in Geriatric Orthopedic Surgery

Last updated: March 27, 2023
Sponsor: National Taiwan University Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Musculoskeletal Diseases

Vascular Diseases

Low Blood Pressure (Hypotension)

Treatment

N/A

Clinical Study ID

NCT05274412
202112163RIND
  • Ages > 60
  • All Genders

Study Summary

Blood pressure optimization has been considered as a crucial factor to avoid perioperative vital organ hypoperfusion, and perioperative hypotension has been addressed as a risk factor for complications and adverse clinical outcomes.

Hypotension prediction index (HPI) is an novel machine-learning derived parameters, and was developed to predict the risk of future hypotension.Series of clinical studies have verified its clinical efficacy in avoiding perioperative hypotension.

Major orthopedic surgeries, such as spine surgery, joint surgery, long bone fracture surgery, are quite common in elder people, who are vulnerable to perioperative adverse outcomes.Thus the investigator design this study to testify the clinical efficacy of implementing HPI in perioperative goal-directed hemodynamic therapy in elder patients receiving major orthopedic surgery.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • adults elder or equal to 60 years old receiving scheduled orthopedic surgery

Exclusion

Exclusion Criteria:

  • Patients with a history of arrhythmia, congestive heart failure, preoperativeneurocognitive disorder, cerebrovascular event, chronic obstructive pulmonary disease,chronic kidney disease, ongoing infectious disease, will be excluded.

Study Design

Total Participants: 280
Study Start date:
March 23, 2022
Estimated Completion Date:
April 30, 2024

Connect with a study center

  • National Taiwan University Hospital

    Taipei,
    Taiwan

    Active - Recruiting

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