Depuy Synthes Lower Extremity Shaft Nail Registry

Inclusion Criteria:

• Skeletally mature adults age greater than or equal to (>=) 22 years (RetrogradeFemoral Nail Advanced [RFNA], Tibial Nail Advanced [TNA]) and adolescents 12-21years of age in which the growth plates have fused (TNA only)

• Participant receives an RFNA and/or TNA based on a diagnosis of open or closed,unilateral or bilateral femoral shaft or distal femur fracture (RFNA); unilateral orbilateral tibial fracture (TNA); revision of malunion or nonunion of previousfracture, or impending pathologic fracture (RFNA only) that will be treatedoperatively as part of standard of care. In addition, the following will beincluded: a) RFNA only: femoral shaft or distal femur fracture can be periprosthetic (PPFx) fracture after total or unicondylar knee arthroplasty, or total or hemi hiparthroplasty requiring nail osteosynthesis

• Participant (legally authorized representative if participant is a minor)voluntarily signs the Institutional Review Board (IRB)/ Ethics committee (EC)approved consent form

• Participant must be able to read and understand questions and responses in anavailable translated language for patient reported outcomes (PROs)

Exclusion Criteria:

• Participation in any other medical device or medicinal product study within theprevious month. Participation in observational studies is allowed

• In the opinion of the Principal Investigator, participant is unable to comply withthe requirements of the Registry

• Participant has known allergies to implant components