A Randomised Comparison of Left and Right Sided Approaches to Ablation of the Atrioventricular Junction

Last updated: January 26, 2022
Sponsor: East Sussex Hospitals NHS Trust
Overall Status: Active - Recruiting

Phase

N/A

Condition

Chest Pain

Dysrhythmia

Arrhythmia

Treatment

N/A

Clinical Study ID

NCT05211453
S001
  • Ages > 18
  • All Genders

Study Summary

This study will compare right sided atrioventricular node ablation to left sided atrioventricular node ablation

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age greater than or equal to 18 years
  • Referred for atrioventricular node ablation for any such indication

Exclusion

Exclusion Criteria:

  • Stroke or transient ischaemic attack (TIA) within 6 months
  • Myocardial infarction within 6 months
  • Medical conditions limiting expected survival to <1 year
  • Moderate to severe aortic stenosis
  • History of aortic or mitral valve replacement
  • Pregnancy or breast feeding women

Study Design

Total Participants: 100
Study Start date:
November 01, 2020
Estimated Completion Date:
November 01, 2022

Study Description

Right-sided atrioventricular node ablation has been the initial conventional approach however up to 18.5% of patients require switching to a left sided approach or have a challenging procedure. Previous studies have found that left sided ablation is more efficacious than right-sided ablation requiring less than 5 applications of radiofrequency energy to induce atrioventricular block.

This study will compare right sided atrioventricular node ablation to left sided atrioventricular node ablation

Connect with a study center

  • Eastbourne District General Hospital

    Eastbourne, East Sussex
    United Kingdom

    Active - Recruiting

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