Is Laparoscopic Excision for Peritoneal Endometriosis Helpful or Harmful?

Last updated: November 13, 2024
Sponsor: University of Aarhus
Overall Status: Active - Recruiting

Phase

N/A

Condition

Endometriosis

Treatment

Laparoscopy without excision

Laparoscopy with excision

Medical treatment-as-usual

Clinical Study ID

NCT05162794
LAPEX
  • Ages 18-50
  • Female

Study Summary

The trial seeks to test effect of laparoscopic excision of peritoneal endometriosis on pelvic pain. Data will also be gathered on quality of life and neuropathic pain. Patients will be randomized to one of three groups: 1) laparoscopy with excision of endometrial tissue, 2) laparoscopy without excision of endometrial tissue and 3) waiting list control.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Adult (≥ 18 years) with suspected peritoneal endometriosis undergoing electivesurgery for pain relief

  • Pain intensity ≥ 5 on Numeric Rating Scale (NRS) in the four weeks prior to givingconsent

Exclusion

Exclusion Criteria:

  • Other known conditions/diseases that may cause pelvic pain

  • Diagnosed personality disorder, schizophrenia or treatment with anti-psychotics

  • Planned pregnancy during study period

  • Women who cannot read or speak Danish

Study Design

Total Participants: 100
Treatment Group(s): 3
Primary Treatment: Laparoscopy without excision
Phase:
Study Start date:
January 31, 2022
Estimated Completion Date:
July 01, 2026

Connect with a study center

  • Regional Hospital Horsens, Department of Obstetrics and Gynecology

    Horsens, Central Jutland Region DK-8700
    Denmark

    Active - Recruiting

  • Aarhus University Hospital, Department of Obstetrics and Gynecology

    Aarhus N, DK-8200
    Denmark

    Active - Recruiting

  • Regional Hospital Herning, Department of Obstetrics and Gynecology

    Herning, DK-7400
    Denmark

    Active - Recruiting

  • Regional Hospital Randers, Department of Obstetrics and Gynecology

    Randers, DK-8930
    Denmark

    Active - Recruiting

  • Regional Hospital Viborg, Department of Obstetrics and Gynecology

    Viborg, DK-8800
    Denmark

    Active - Recruiting

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