Evaluation of Sensitization to Peach and/or Cypress in Potato Sensitized Patients in a Large Cohort

Last updated: November 12, 2021
Sponsor: University Hospital, Montpellier
Overall Status: Active - Recruiting

Phase

N/A

Condition

Common Cold

Allergy (Pediatric)

Nasal Obstruction

Treatment

N/A

Clinical Study ID

NCT05119478
RECHMPL21_0612
  • Ages 2-99
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The aim of the study will be to investigate the prevalence of of sensitization to peach and/or cypress in potato sensitized patients, based on the collection of medical data from patient records consulting in the Allergy Unit of the Arnaud de Villeneuve Hospital.

Some Gibberellin-regulated protein (GRP) in fruits and pollens have been identified as allergen, and peach GRP (peamaclein) has recently emerged as a relevant food allergen in cypress pollen-hypersensitive patients. Multiple fruit allergies might be related to cross-reactivity between GRPs. Peamaclein shares 82% identity with snakin-1 from potato. Thus, because of this hight homology the investigators want to determine the prevalence of cosensitization between these 3 allergens potato, peach and cypress.

Eligibility Criteria

Inclusion

Inclusion criteria:

  • Patients evaluated at the Montpellier University Hospital, Allergy Unit
  • children and adult with positive skin prick test to potato from february 2013 todecember 2015

Exclusion

Exclusion criteria:

  • Patients under legal protection
  • Patients under guardianship or under curatorship
  • Patients not capable of understanding French

Study Design

Total Participants: 594
Study Start date:
October 01, 2021
Estimated Completion Date:
April 01, 2022

Connect with a study center

  • Uhmontpellier

    Montpellier, 34295
    France

    Active - Recruiting

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