Role of Gut Microbiome in Cancer Therapy

Last updated: December 3, 2024
Sponsor: Mayo Clinic
Overall Status: Active - Recruiting

Phase

N/A

Condition

Neoplasms

Treatment

Electronic Health Record Review

Biospecimen Collection

Clinical Study ID

NCT05112614
19-003060
NCI-2021-10793
  • Ages 18-99
  • All Genders

Study Summary

This study examines how gut microbiome can affect cancer therapy in cancer patients undergoing cancer therapy or stem cell transplant. The human microbiome affects the way some cancer drugs are metabolized in the human body. Information from this study may help doctors improve the way cancer treatment is delivered, and increase its effectiveness and success.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age 18-99

  • Diagnosis of cancer and undergoing cancer therapy or scheduled to start cancertherapy or undergoing stem cell transplant for any hematological condition

Exclusion

Exclusion Criteria:

  • Unable to provide informed consent

  • Vulnerable adults

Study Design

Total Participants: 5000
Treatment Group(s): 2
Primary Treatment: Electronic Health Record Review
Phase:
Study Start date:
September 11, 2019
Estimated Completion Date:
October 01, 2030

Study Description

PRIMARY OBJECTIVE:

I. To correlate gut microbiome with specific cancer diagnoses and the clinical response (efficacy), and adverse effects of cancer therapy (single or multiple) and stem cell transplant.

OUTLINE:

Patients undergo collection of blood and stool samples and have their medical records reviewed.

Connect with a study center

  • Mayo Clinic in Arizona

    Scottsdale, Arizona 85259
    United States

    Site Not Available

  • Mayo Clinic in Florida

    Jacksonville, Florida 32224
    United States

    Site Not Available

  • Mayo Clinic in Rochester

    Rochester, Minnesota 55905
    United States

    Active - Recruiting

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