Expanded Access Protocol for Patients With Eosinophilic Esophagitis

Inclusion Criteria:

1. Male or female ≥12 years of age at the time of informed consent

2. Signed ICF and willing and able to adhere to all procedures; signed assent form andparent/guardian ICF must also be collected for adolescents

3. Confirmed medical history of EoE

4. Adult and adolescent patients who are unable or ineligible to enroll in an APT-1011clinical study or have failed available treatment options

5. Willing and able to adhere to the treatment regimen and visit schedule

Exclusion Criteria:

1. Have known contraindication, hypersensitivity, or intolerance to corticosteroids

2. Have signs and symptoms of adrenal suppression or hypercorticism

3. Use of potent CYP3A4 inhibitors (e.g., ritonavir and ketoconazole) are prohibited

4. Have current alcohol or drug abuse in the opinion of the Investigator

5. Female patients who are pregnant, breastfeeding, or planning to become pregnantwhile participating in the program

6. Female patients of child-bearing potential who are unable to comply with adequatecontraception use during the program