Knee Nerve Cryoneurolysis and Impact on Pain After Prosthetic Surgery

Inclusion Criteria:

• Age ≥ 18 years and ≤ 80 years;

• Patient to undergo prosthetic knee surgery;

• Patient in good health (ASA score 1 to 3);

• Patient able to understand the information related to the study, read theinformation leaflet and agree to sign the consent form.

Exclusion Criteria:

• Known intolerance to any of the products administered during surgery orcryoneurolysis;

• Patient with an electric implant;

• Patient with a contraindication to cryoanalgesia (coagulation disorders, infections,nerve damage);

• Drug addict patient;

• Intervention on septic bone;

• Chronic renal failure (creatinine clearance <30 mL / min);

• History of cryoglobulinemia, cold urticaria or Raynaud's syndrome;

• Pregnant or breastfeeding woman;

• Patient under guardianship or curatorship, or under a regime of deprivation ofliberty;

• Patient participating in another clinical trial, or in a period of exclusion fromanother clinical trial;

• Patient not beneficiary of a social security scheme.