Separation Versus Integrated Approach in Combining ECMO With CRRT

Last updated: August 13, 2025
Sponsor: Chulalongkorn University
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Combination of extracorporeal membrane oxygenation and continuous renal replacement therapy

Clinical Study ID

NCT05036616
IRB.151/64
  • Ages 18-90
  • All Genders

Study Summary

This investigation aims to evaluate the filter life time of CRRT membrane and complication of combining ECMO and CRRT.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. > 18 years

  2. Refractory acidosis (pH<7.2 or HCO3<15)

  3. Refractory volume overload

  4. Refractory hyperkalemia (K>6.2mEq/L or EKG change)

  5. Anuria or oliguria (urine output <0.5 mL/kg/hr for 6-12hr)

  6. High BUN >100 mg/dL or uremic symptom

  7. Increase intracranial pressure

Exclusion

Exclusion Criteria:

  1. Pregnancy

  2. Not use heparin in ECMO

  3. Chronic kidney disease with CRRT

  4. AKI with Glomerulonephritis, Interstitial nephritis, Vassculitis or Urinary tractobstruction

Study Design

Total Participants: 40
Treatment Group(s): 1
Primary Treatment: Combination of extracorporeal membrane oxygenation and continuous renal replacement therapy
Phase:
Study Start date:
April 01, 2021
Estimated Completion Date:
August 31, 2026

Connect with a study center

  • Sasipha tachaboon

    Bangkok, 10330
    Thailand

    Active - Recruiting

Map preview placeholder

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.