CBT for Youth With Autism and Emotional/Behavioral Needs in Community Care Settings

Last updated: June 8, 2024
Sponsor: University of California, Los Angeles
Overall Status: Active - Recruiting

Phase

N/A

Condition

Autism

Autism Spectrum Disorder (Asd)

Treatment

Treatment-as-Usual Supplemented by Internet-Based Self-Instruction (MEYA)

Behavioral Interventions for Anxiety in Children with Autism (BIACA)

Clinical Study ID

NCT05031364
AR200108
  • Ages 6-14
  • All Genders

Study Summary

This study is a 4-year randomized, controlled trial comparing cognitive behavioral therapy (CBT) to usual clinical care for children (aged 6-14 years) with autism and emotional dysregulation (e.g., irritability, anxiety). We will randomly assign 50 mental health clinicians, each treating 2 youth (N = 100 youth total), to CBT program for emotional dysregulation and core autism symptoms with weekly live consultation with an expert or to usual clinical care augmented by self-instruction in CBT, in a 1:1 allocation. The CBT manual is well-supported in our efficacy research, has been replicated in other centers, is free/open-access (meya.ucla.edu), and has user-friendly digital and traditional print materials for mental health clinicians (e.g., psychologists, counselors) to use in preparing for and conducting therapy sessions. The primary outcome measure will be assessed weekly. Additional assessments will occur at Screening, Mid-treatment, Post- treatment and 3-month Follow-up.

Eligibility Criteria

Inclusion

Clinician's inclusion criteria: All practitioner participants will regularly treat at least some youth with ASD within a recognized field of practice (e.g., clinical psychology, counseling, marital and family therapy, social work) and will serve youth with ASD referred by the Regional Centers, Tricare/NMCSD, or the California public schools. Practitioners will agree to invite one or more potentially eligible families of youth with ASD so that, in total, at least 2 of the new families referred to them participate in the study (i.e., each clinician will aim to have a cluster of two families randomized to the same condition with them; however, the two referrals can be non-parallel and clinicians will not be required to enroll a second client to remain in the study, since there is no way for them to guarantee future enrollment from client families. As needed, additional clinicians can be enrolled in the study to reach the target of 100 youth.). Up to four families per practitioner will be allowed so long as the minimum study enrollment of at least 50 practitioners and 100 client families randomized is met.

Youth inclusion criteria: Youth participants will be boys or girls between 6 and 14 years of age with a documented clinical diagnosis of ASD and will be newly referred for outpatient services with a participating clinician. Additional eligibility criteria are as follows:

  1. Youth will have a pre-existing clinical diagnosis of ASD made by an appropriatelicensed professional (e.g., clinical psychologist, developmental pediatrician)which will be documented in a report or medical note provided by the family, orconfirmed telephonically by the diagnosing professional.

  2. The parent-reported Social Responsive Scale-2 (SRS-2; Constantino & Gruber, 2012)Total T-Score will be > 60 (cut-score maximizing ROC curve parameters for screeningfor ASD; area under the curve = 98.8%; Schanding et al., 2011).

  3. Youth will meet criteria for clinically significant emotion dysregulation symptomsas defined by a minimum T-score of 60 on the Externalizing or Internalizingsubscales of the parent-reported Brief Problem Monitor (BPM) and at least 15 T-scorepoints over 50 between these two BPM subscales (e.g., Internalizing=60 +Externalizing=55).

  4. The youth has a Vineland Adaptive Behavior Scales-3 Communication Composite StandardScore > 60 and Expressive Communication subscale v-score > 8 (in both cases > 1st %ile).

Exclusion

Exclusion Criteria:

  1. For participants presenting with severe comorbid symptomology (e.g., psychoticsymptoms), the comorbid conditions cannot be sufficiently severe to warrantimmediate treatment or require ongoing medication titration.

Study Design

Total Participants: 100
Treatment Group(s): 2
Primary Treatment: Treatment-as-Usual Supplemented by Internet-Based Self-Instruction (MEYA)
Phase:
Study Start date:
July 01, 2021
Estimated Completion Date:
June 30, 2026

Connect with a study center

  • Westside Regional Center

    Culver City, California 90024
    United States

    Active - Recruiting

  • California Autism Professional Training and Information Network (CAPTAIN)

    Sacramento, California 95817
    United States

    Active - Recruiting

  • Naval Medical Center San Diego

    San Diego, California 92115
    United States

    Active - Recruiting

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