Assessment of Postoperative Pain After Using Two Formulations of Calcium Hydroxide Intracanal Medication .

Last updated: March 20, 2022
Sponsor: Suez Canal University
Overall Status: Active - Recruiting

Phase

4

Condition

Periodontitis

Treatment

N/A

Clinical Study ID

NCT05021809
360/2021
  • Ages > 18
  • All Genders

Study Summary

Calcium hydroxide is advocated as an intracanal medication for various purposes, including prevention of post-treatment symptoms. Calcium hydroxide has a pain-controlling effect at different times when compared to non-intracanal medication .

Aim:

The aim of the study to compare between postoperative pain after using two formulations of calcium hydroxide intracanal medication with and without iodoform .

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • .single-rooted teeth with pulpal necrosis and symptomatic apical periodontitis withvisible radiographic disturbance of periapical lamina dura. The diagnosis of pulpnecrosis was confirmed by negative response to cold test, electric pulp tester andclinically by absence of blood upon access cavity .
  • Clinical signs of apical periodontitis.
  • Teeth with sufficient coronal tooth structure for adequate rubber dam isolation wereselected .
  • Patients who are over 18 years old .

Exclusion

Exclusion Criteria:

  • Presence of open apices
  • Presence of non-restorable teeth
  • Presence of large carious lesions approaching the root.
  • Presence of calcification or resorption .
  • Patients who had received antibiotics during the last 3 months .
  • Teeth with periodontal probing depth > 4 ml.
  • Teeth with previous root canal treatment .
  • Teeth with fluctuant facial swelling .
  • Pregnant females.

Study Design

Total Participants: 60
Study Start date:
July 25, 2021
Estimated Completion Date:
November 30, 2022

Study Description

The most persuasive factor for a patient to visit a dental health care professional is the existence of odontalgia. Accordingly, the pain after a dental therapy results in demotivation of the patient. Unfortunately, mild to severe pain following a tooth-preserving therapy such as root canal treatment is reported to be experienced by 40% of the patients.

The majority of patients with symptomatic necrotic teeth had significant postoperative pain and required analgesic medication to manage this pain.

There is a correlation between the intensity of preoperative pain and postoperative pain ,The preoperative pain has a significant influence on postoperative pain.

Several strategies are suggested to manage or prevent post instrumentation pain. One of them is insertion of intracanal medicament.

The interappointment intracanal medicaments are suggested for disinfection of the infected root canal system in multi-visit endodontic treatment. Calcium hydroxide (Ca(OH)2) is considered as a universal intracanal medicament for this purpose.

Additionally, calcium hydroxide is hypothesized to exert a pain-preventing effect indirectly through its antimicrobial and tissue modifying properties .

Significantly high healing rates have been shown with short term use of calcium hydroxide Ca(OH)2 in teeth with apical periodontitis. As a temporary root filling, it has been shown to be an effective antimicrobial agent when applied for a minimum of 1 week.

Calcium hydroxide is a suitable material of choice as an inter-appointment dressing for teeth diagnosed with pulpal necrosis and apical periodontitis.

Calcium hydroxide reduced pain risk than no intracanal medication within the 1-14 days interval as well as triple-antibiotic paste within the first day and was similar to corticosteroid/antibiotics combination.

Iodoform has bacteriostatic property by releasing free iodine.Thereby, iodine eliminates the infection of root canal and periapical tissue by precipitating protein and oxidizes essential enzymes.

The use of calcium hydroxide-iodoform-silicon-oil paste as nonsurgical approach for treatment of periapical lesions showed a high success rate.

As clinicians , one of the most important goals to achieve is reducing the pain of the patient. Up to our knowledge, none of the previous studies investigated the postoperative pain incidence after application of Ca(OH)2 with iodoform as an intracanal medication .

Connect with a study center

  • Endodontic Clinic At Faculty of Dentistry ,Suez Canal University

    Ismailia, 41511
    Egypt

    Active - Recruiting

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