Catalyst CSR Shoulder System for Semi or Total Shoulder Arthroplasty

Last updated: August 19, 2024
Sponsor: Catalyst OrthoScience
Overall Status: Active - Recruiting

Phase

N/A

Condition

Joint Injuries

Osteoarthritis

Rheumatoid Arthritis

Treatment

Catalyst CSR Total Shoulder System

Clinical Study ID

NCT04968405
1226-9272-01
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Evaluation of the performance and safety of the Catalyst CSR Shoulder System with clinical and radiographic results at multiple time points through 24 months postoperatively This study will be a prospective multi-center study conducted in the United States.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • 18 years of age or older

  • Patient must be skeletally mature with degenerative disease of the glenohumeral joint where hemi or total shoulder arthroplasty

  • Meets the Catalyst CSR Shoulder System Indications for Use according to approved labeling

Exclusion Criteria

  • Has a history of open surgery to index shoulder prior to treatment with the Catalyst CSR system? (history of previous arthroscopic surgery allowed)

  • Has a full thickness rotator cuff tear diagnosed by MFI or marked posterior glenoid wear

  • Patient is unwilling or unable to comply with the post-operative care instructions, attend follow visits per the study schedule and complete the study assessments (i.e., Pros)

  • The patient is a non-English speaker

  • In the opinion of the investigator, is it not in the patient's best interest to participate in this study

  • Local or systemic infection, or osteomyelitis of the proximal humerus or scapula; if a systemic infection or a secondary remote infection is suspected or confirmed, joint replacement surgery should be delayed until infection is resolved

  • Inadequate or malformed bone that precludes adequate support of fixation of the prosthesis

  • Osteoporosis

  • Neuromuscular disorders that do not allow control of the joint

  • Chronic instability, chronic dislocation or deficient soft tissues and other support structures (e.g., brachial plexus or deltoid muscles)

  • Vascular insufficiency

  • Subject's age, weight or activity level cause the surgeon to expect early failure of the system

  • The patient is unwilling to comply or unable to comply with the post-operative care instructions

  • Alcohol, drug, substance abuse or other conditions that would affect or impair the patient from complying with post-operative instructions

  • Patients with known sensitivity to Co-Cr-Mo alloys typically used prosthetic devices

  • Any disease that could adversely affect the function or expected longevity of the implants (e.g., metabolic disorders)

Study Design

Total Participants: 90
Treatment Group(s): 1
Primary Treatment: Catalyst CSR Total Shoulder System
Phase:
Study Start date:
July 22, 2022
Estimated Completion Date:
February 28, 2026

Study Description

The purpose of this study is to assess the performance and safety of the Catalyst CSR Shoulder System in skeletally mature patients with degenerative disease of the glenohumeral joint where hemi or total shoulder arthroplasty is determined by the surgeon to be the preferred method of treatment. Patients who sign informed consent and meet the inclusion/exclusion criteria will have the Catalyst CSR Shoulder system implanted at participating sites. Data will be collected at baseline (pre-operative), perioperatively, and postoperatively at 3 months, 6 months, 12 months and 24 months. This study is expected to take 36 months to complete.

Connect with a study center

  • Beaumont Hospital Royal Oak

    Royal Oak, Michigan 48073
    United States

    Active - Recruiting

  • Kaiser Permanente Northwest Center for Health Research

    Portland, Oregon 97227
    United States

    Active - Recruiting

  • Lifespan/University Orthopedics

    Providence, Rhode Island 02914
    United States

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.