Tracheal Intubation in COVID-19 Patients

Last updated: June 1, 2021
Sponsor: St. Bortolo Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Pneumonia

Covid-19

Endotracheal Intubation

Treatment

N/A

Clinical Study ID

NCT04909476
125/20
  • Ages > 18
  • All Genders

Study Summary

The Emergency Endotracheal intubation of a patient who is COVID-19 positive is a high-risk procedure and an additional challenge to an intensivist due to barrier enclosures that have been developed to reduce the risk of COVID-19 transmission to healthcare providers during intubation. Although the incidence of difficult airways is commonly higher in critically ill patients, the evidence of severe hypoxemia without sign of respiratory distress could complicate the scenario.This silent hypoxia often leads to a delayed recognition of the severity of respiratory failure and to a late intubation which is often characterized by a high risk of complications related to the actual airways' management, hemodynamic and cardiac. It has been shown that non-survivors had worse blood gas analyzes than survivors, both before and after intubation. Few studies have reported the implications and adverse events of performing endotracheal intubation for critically ill COVID-19 patients admitted to intensive care units (ICUs).

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Critically ill patient above 18 year old, admitted in the Intensive Care of SanBortolo Hospital, Vicenza, and San Matteo Hospital, Pavia;
  • positive specimen for SARS-COV2 PCR;
  • tracheal intubation for respiratory distress related to SARS COV2 pneumonia

Exclusion

Exclusion Criteria:

  • negative specimen for SARS-COV2 PCR
  • out of hospital intubation
  • intubation during cardiac arrest
  • intubation in the contest of general anesthesia for surgery

Study Design

Total Participants: 143
Study Start date:
November 17, 2020
Estimated Completion Date:
June 10, 2021

Connect with a study center

  • San Matteo Hospital

    Pavia, Lombardia 27100
    Italy

    Active - Recruiting

  • San Bortolo Hospital

    Vicenza, Veneto 36100
    Italy

    Active - Recruiting

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