Severe Acquired Brain Injuries: Prognostic Factors and Quality of Care

Last updated: February 20, 2025
Sponsor: Mario Negri Institute for Pharmacological Research
Overall Status: Active - Recruiting

Phase

N/A

Condition

Neurologic Disorders

Treatment

N/A

Clinical Study ID

NCT04905264
TIRESIA
  • Ages > 18
  • All Genders

Study Summary

The main purpose of this project is to identify the medium-term prognostic factors for patients with Severe Acquired Brain Injuries and evaluate their impact.

The secondary aim is to create a system of continuous assessment of the quality of care for each rehabilitation unit.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • patients with Serious Acquired Brain Injuries

  • admission to rehabilitation units

Exclusion

Exclusion Criteria:

  • patients admitted more than 14 weeks after the acute event

Study Design

Total Participants: 2500
Study Start date:
January 03, 2022
Estimated Completion Date:
June 30, 2025

Study Description

For each unit involved, it will be collected these data :

  • Structural and organizational data of the Rehabilitation Units for Severe Acquired Brain Injuries;

  • Detailed information on patients upon entering Rehabilitation Units for Severe Acquired Brain Injuries;

  • Detailed information on patients, re-evaluated 4 months after the acute event

Statistical models will be implemented, in order to identify prognostic factors that could predict the probability to observe three events, which represent objectives of the rehabilitation process: decannulation, trunk control and total feeding by os. These events should be evaluated four months after the acute episode.

Connect with a study center

  • Ospedale SS. Antonio e Biagio e C. Arrigo

    Alessandria, 15121
    Italy

    Active - Recruiting

  • Centro di Riabilitazione Terranuova Bracciolini

    Arezzo, 52025
    Italy

    Active - Recruiting

  • Ospedale civile di Baggiovara

    Baggiovara, 41126
    Italy

    Active - Recruiting

  • ASST Papa Giovanni XXIII

    Bergamo,
    Italy

    Active - Recruiting

  • Ospedale Maggiore

    Bologna, 40133
    Italy

    Active - Recruiting

  • Fondazione Poliambulanza

    Brescia, 25124
    Italy

    Active - Recruiting

  • Ospedale S. Michele, AO Brotzu

    Cagliari, 09047
    Italy

    Site Not Available

  • Ospedale S. Sebastiano

    Correggio, 42015
    Italy

    Active - Recruiting

  • Istituto S. Anna

    Crotone, 88900
    Italy

    Active - Recruiting

  • Azienda Ospedaliero-Universitaria di Ferrara

    Ferrara, 44124
    Italy

    Active - Recruiting

  • Fondazione Don Gnocchi

    Firenze,
    Italy

    Active - Recruiting

  • Ospedale di Foligno

    Foligno, 06034
    Italy

    Site Not Available

  • Montecatone Rehabilitation Institute SpA

    Imola,
    Italy

    Active - Recruiting

  • USL Toscana Nord Ovest

    Lucca, 55100
    Italy

    Active - Recruiting

  • IRCCS S. Maria Nascente, Fondazione don Gnocchi

    Milano, 20148
    Italy

    Active - Recruiting

  • Istituto Palazzolo, Don Gnocchi

    Milano, 20149
    Italy

    Site Not Available

  • Ospedale Sacro Cuore don Calabria

    Negrar, 37024
    Italy

    Active - Recruiting

  • ATS Sardegna

    Oristano, 09170
    Italy

    Site Not Available

  • Ospedale Buccheri La Ferla Fatebenefratelli

    Palermo, 90123
    Italy

    Site Not Available

  • Centro Cardinal Ferrari

    Parma, 43012
    Italy

    Site Not Available

  • AUSL Piacenza

    Piacenza,
    Italy

    Active - Recruiting

  • Centro di riabilitazione E. Spalenza, Don Gnocchi

    Rovato, 25038
    Italy

    Active - Recruiting

  • Ospedale "Casa Sollievo della Sofferenza"

    San Giovanni Rotondo,
    Italy

    Active - Recruiting

  • Fondazione Don Gnocchi, Sant'Angelo dei Lombardi

    Sant'Angelo Dei Lombardi,
    Italy

    Active - Recruiting

  • IRCCS Telese, ICS Maugeri

    Telese Terme, 82037
    Italy

    Site Not Available

  • Ospedale Riabilitativo Villa Rosa

    Trento, 38057
    Italy

    Active - Recruiting

  • A.ULSS n.8 Berica

    Vicenza, 36100
    Italy

    Active - Recruiting

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