Radiocontrast Media in the Pulsed Radiofrequency Treatment

Last updated: May 3, 2021
Sponsor: Sanliurfa Education and Research Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Radiculopathy

Lower Back Pain

Peripheral Neuropathy

Treatment

N/A

Clinical Study ID

NCT04876469
01.02.2021-E.7779
  • Ages 18-65
  • All Genders

Study Summary

Pulsed radiofrequency applied to the dorsal root ganglion (DRG) is an interventional treatment alternative in the treatment of lumbar radicular pain that does not respond to conservative methods. Under intermittent fluoroscopic imaging, the location of the ganglion can be determined by administering contrast media. We consider that determining the localization of the ganglion with this method during pulse radiofrequency application can shorten the procedure time. In this way, we believe that it would help the correct application of the procedure.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • 18-65 years of age.
  • Lumbar radicular pain
  • Lack of response to conservative methods
  • L5 nerve root compression due to disc herniation

Exclusion

Exclusion Criteria:

  • Patients younger than 18 and older than 65
  • Non-radicular low back pain
  • L5 nerve root compression due to reasons other than disc herniation
  • Those having spondylolisthesis, or transitional vertebra
  • Having an active infection
  • Pregnancy
  • Bleeding diathesis
  • Renal Insufficiency

Study Design

Total Participants: 60
Study Start date:
March 01, 2021
Estimated Completion Date:
July 01, 2021

Study Description

Although there are many reasons that can lead to low back pain, radicular pain, which is mostly secondary to lumbar disc hernia, is one of the most common pathologies. Pulsed radiofrequency applied to the dorsal root ganglion (DRG) is an interventional treatment alternative in the treatment of lumbar radicular pain that does not respond to conservative methods and epidural injection treatments.

The electrical field created by the application of pulsed radiofrequency (PRF) changes the cellular activity in DRG neurons. By polarizing cell membranes, reduces nociceptive transmission and contributes to analgesia. In lumbar dorsal root ganglion PRF applications, when the targeted point is reached, the position is confirmed by giving motor and sensory stimuli, and the PRF application is initiated in the follow-up. However, it is a problem that the DRG is not always in the same location, and therefore, time is often lost or even not found while searching with stimulation. Under intermittent fluoroscopic imaging, the location of the ganglion can be determined by administering contrast material.

We consider that determining the localization of the ganglion with this method during pulse radiofrequency application can shorten the procedure time. In this way, we believe that it would help the correct application of the procedure.

Connect with a study center

  • Sanliurfa Education and Research Hospital

    Sanliurfa,
    Turkey

    Active - Recruiting

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