Adapting Anxiety Intervention for Youth With Autism for Rapid Response to COVID-19

Last updated: July 14, 2025
Sponsor: Holland Bloorview Kids Rehabilitation Hospital
Overall Status: Completed

Phase

N/A

Condition

Williams Syndrome

Asperger's Disorder

Autism Spectrum Disorder (Asd)

Treatment

Cognitive behavior therapy (CBT), specifically using the Facing Your Fears (FYF) curriculum

Clinical Study ID

NCT04666493
0240
  • Ages 8-13
  • All Genders

Study Summary

This study will examine if a virtual delivery of a group Cognitive Behavioural Therapy (CBT) program, specifically using "Facing Your Fears" (FYF) curriculum, is helpful in improving anxiety symptoms for children and youth with ASD. This study will adapt the FYF program for virtual delivery using a platform called "Zoom for Healthcare" and examine its effectiveness.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Chronological age between 8 and 13 years (13 yr, 11 mos, 29 days)

  2. Have a clinical diagnosis of Autism Spectrum Disorder (ASD)

  3. Ability to read at a grade 2 level or above (based on parent report)

  4. Verbally fluent at a grade 2 level or above (can speak or respond to questions thatare appropriate for a child in grade 2; based on parent report)

  5. Child with significant anxiety symptoms as determined by the clinical team

  6. To enhance generalizability of our findings, children will be eligible if theypresent with some other co-morbid psychiatric conditions (see exclusion criteria)

  7. If already receiving pharmacological interventions, must meet the followingcriteria: If receiving concomitant medications for anxiety, must be on a stable doseduring the month prior to screening (6 weeks for fluoxetine).

Exclusion

Exclusion Criteria:

  1. Being currently enrolled in another active behavioral/ educational/ psychologicaltreatment for anxiety

  2. Diagnosis of acute psychosis or conduct disorder, or a primary diagnosis ofObsessive Compulsive Disorder without another anxiety diagnosis or clinicallysignificant level of anxiety.

Study Design

Total Participants: 101
Treatment Group(s): 1
Primary Treatment: Cognitive behavior therapy (CBT), specifically using the Facing Your Fears (FYF) curriculum
Phase:
Study Start date:
December 04, 2020
Estimated Completion Date:
January 30, 2022

Study Description

The research team will adapt the Facing Your Fears (FYF) program, in consultation with program developers, Canadian experts (psychologists) and Holland Bloorview's Research Family Engagement Committee, to allow for virtual delivery of a traditionally in-person intervention. Adaptations will build on preliminary work already piloted by program developers to meet the current needs (e.g., group work with individual support, video practice for exposures, psychoeducation format).

Participants will complete one screening phone call and one videoconferencing (Zoom for Healthcare) call with the research team, where the delegated research staff will introduce the program and obtain consent for interested and eligible participants. Participants will be asked to provide consent, then proceed to the second part of the screening to ensure that potential participants meet all eligibility criteria. It will be made clear to participants that providing consent and assent at this time will not guarantee study enrollment.

Once eligibility is confirmed, participants will be enrolled in the study and be asked to provide the study team with the participant's ASD diagnostic letter via a secure link (using Sync), complete pre-intervention questionnaires before the start of the program, and post-intervention questionnaires after completing the study intervention.

The program will be abbreviated from 14 weeks to 12 weeks to maximize the number of families served during the study period. Each session will be approximately 60-90 minutes (30-45 minutes with parents and children; 30-45 minutes with parents alone). There will be two check-in calls (approximately 30 mins) with each of the families after weeks 7 and 9 of the program. The group facilitators will use the Zoom for Healthcare platform to deliver the intervention virtually.

Connect with a study center

  • Holland Bloorview Kids Rehabilitation Hospital

    Toronto, Ontario M4G 1R8
    Canada

    Site Not Available

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