Application of Chinese Herbal Complementary and Alternative Medicine (CAM) to Improve Human Health and to Further Botanical and Horticultural Sciences

Inclusion Criteria:

• Female subjects with newly diagnosed breast carcinoma

• > 18 years of age

• Post-mastectomy with or without reconstruction

• Stage II-IIIb with any receptor status

• All races and ethnicities are eligible

• Patients must be able to consent in English or Spanish

• Plan to receive adjuvant radiotherapy to the chest wall +/- regional lymph nodes

• RT will involve standard fractionation use of 3D conformal or Intensity-modulated RT (IMRT)

• Willing to sign protocol consent form

• Patients are allowed to receive adjuvant hormonal therapy and/or targeted therapiessuch as trastuzumab prior to, during and/or after radiation therapy.

• Patients may receive chemotherapy before or after radiation therapy

Exclusion Criteria:

• Prior radiation to the involved breast or chest wall

• Concurrent chemotherapy

• Unable or unwilling to sign informed consent

• Unable to speak English or Spanish

• Pregnant women

• Clinical or pathologic stage T4

• Metastatic disease

• Connective tissue disorder including Systemic Lupus Erythematosus and Scleroderma