Alveolar Ridge Preservation Following Tooth Extraction Using Advanced Platelet Rich Fibrin (A-PRF) Versus Platelet Rich Fibrin (PRF)

Last updated: January 28, 2021
Sponsor: Cairo University
Overall Status: Active - Enrolling

Phase

N/A

Condition

Bone Density

Treatment

N/A

Clinical Study ID

NCT04434703
6-3-1
  • Ages 20-60
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

the aim of this study is clinically and radiographically evaluate the use of advance platelet rich fibrin (A-PRF) versus platelet rich fibrin (PRF) in preservation of alveolar ridge following tooth extraction

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients with at least one non restorable tooth in upper inter-bicuspid region.
  • Stable periodontal condition with no acute periapical infection.
  • Systematically healthy conditions.
  • Cooperative patients.
  • Intact buccal plate of bone.

Exclusion

Exclusion Criteria:

  • Smokers.
  • Patients seeking immediate or early implants.
  • Pregnant females.
  • Bone diseases.
  • Drugs and diseases that may affect platelet count or function.

Study Design

Total Participants: 60
Study Start date:
November 01, 2020
Estimated Completion Date:
September 01, 2021

Study Description

systemically healthy patients who have at least one non-restorable tooth in the upper inter-bicuspid region and are not seeking immediate or early implant treatment will be allocated in this study after performing nonsurgical periodontal therapy and preoperative periapical therapy to evaluate and improve the condition of the periodontal tissues.

Anesthesia will be given then flapless atraumatic extraction using periotomes followed by forceps after luxation. For all groups, the socket will be debrided using curette then

  • group A, the socket will be filled with A.PRF

  • group B the socket will be filled with PRF.

  • group C no bio-additive will be added.

  • Criss cross horizontal mattress suture will be applied to close the extraction wound.

PRF and A-PRF preparation :

10 ml of blood will be drawn from each patient by vein puncture of the antecubital vein.

  • Plateletr ich fibrin (PRF) is 3000 rpm and 10 minutes without addition of anticoagulant

  • Advanced platelet rich fibrin (A-PRF) is 1300 rpm and 8 minutes.

Connect with a study center

  • School of dentistry , Cairo University

    Cairo, 11865
    Egypt

    Site Not Available

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