Functional Changes in the Stomach and Esophagus After One Anastomosis Gastric Bypass- OAGB

Last updated: June 3, 2025
Sponsor: Spital Limmattal Schlieren
Overall Status: Active - Recruiting

Phase

N/A

Condition

Ulcers

Treatment

One Anastomosis Gastric Bypass (OAGB)

Clinical Study ID

NCT04422405
SLS-003
  • Ages 18-65
  • All Genders

Study Summary

Evaluation of the functional changes in the stomach and esophagus of patients undergoing One Anastomosis Gastric Bypass (OAGB)

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • BMI> 35 kg/m2

  • 2 years of controlled conservative obesity treatment without weight reduction

  • patients should give their consent to participate in the study

Exclusion

Exclusion Criteria:

  • Less than 2 years of conservative obesity treatment

  • cancer

  • cirrhosis Child-Pough score A

  • Crohn's disease

  • serious psychiatric disorder, which led to in-hospital treatment in psychiatricclinic in the past two years

  • drug consumption

  • non-compliance

  • hiatal hernia > 4cm

  • gastric pouch < 10cm

  • Barett esophagus

  • erosive esophagitis Grade C or D according to the Los Angeles Classification

  • endoscopically proven gastric stricture

  • acid exposition time > 6% (Lyon criteria)

  • reflux episodes> 80 /24 hours (Lyon criteria)

  • insufficient low esophageal sphincter according to manometry findings

  • pathological findings in the impedance pH-metry (acid and non-acid reflux)

Study Design

Total Participants: 300
Treatment Group(s): 1
Primary Treatment: One Anastomosis Gastric Bypass (OAGB)
Phase:
Study Start date:
June 01, 2020
Estimated Completion Date:
May 28, 2035

Connect with a study center

  • Limmattal Hospital

    Schlieren, Zurich 8952
    Switzerland

    Active - Recruiting

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