A Randomized Controlled Trial to Evaluate the Efficacy of Acupuncture Versus Aromatherapy as Treatments to Lessen Nausea, Vomiting and Anxiety Associated With Adriamycin and Cytoxan

Last updated: April 11, 2025
Sponsor: Englewood Hospital and Medical Center
Overall Status: Completed

Phase

N/A

Condition

Lactose Intolerance

Mood Disorders

Vomiting

Treatment

Acupuncture

Aromatherapy

Clinical Study ID

NCT04116697
E-19-773
  • Ages > 18
  • Female

Study Summary

The overall goal of this study is to explore the effectiveness of using acupuncture versus aromatherapy, in conjunction with standard of care anti-emetics, to decrease chemotherapy induced nausea, vomiting, and anxiety in breast cancer patients undergoing Adriamycin and Cytoxan. This study also aims to determine if aromatherapy and anti-emetics is more effective than acupuncture and anti-emetics in treating nausea, vomiting, and anxiety in patients receiving Adriamycin and Cytoxan and if acupuncture and anti-emetics is more effective than aromatherapy and anti-emetics in treating nausea, vomiting, and anxiety in patients receiving Adriamycin and Cytoxan.

Eligibility Criteria

Inclusion

i) Inclusion

  • At least 18 years of age on the day of signing informed consent

  • Patient has a diagnosis of breast cancer

  • Patient is planned to start Adriamycin and Cytoxan chemotherapy

ii) Exclusion

  • Patients who are unable to adhere to the protocol or treatment schedule

  • Patients who have a concurrent illness or take medication that induces nausea independent of chemotherapy

  • Patients undergoing radiotherapy or hormone therapy during chemotherapy treatments

  • Patients who have a sensitive and/or poor sense of smell

  • Patients who are allergic to essential oils, specifically peppermint, ginger, and/or lavender

  • Patients who are already using essential oils or acupuncture for symptom management and are unwilling to stop while participating in this study

  • Patients who are afraid of or unwilling to receive acupuncture stimulation

  • Patients who are allergic to stainless steel needles

  • Thrombocytopenia (Platelets < 20,000)

  • Patients who have received aromatherapy and/or acupuncture treatment within 1 week of starting treatment on this study

Study Design

Total Participants: 26
Treatment Group(s): 2
Primary Treatment: Acupuncture
Phase:
Study Start date:
October 23, 2019
Estimated Completion Date:
October 01, 2024

Connect with a study center

  • Englewood Health

    Englewood, New Jersey 07631
    United States

    Site Not Available

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