EXplanted LIver and Ex-vivo Pancreatic Specimen Evaluation by 7 TESLA MRI

Last updated: July 4, 2019
Sponsor: University of Pisa
Overall Status: Active - Recruiting

Phase

N/A

Condition

Pancreatic Cancer

Liver Cancer

Pancreatitis

Treatment

N/A

Clinical Study ID

NCT04012021
13646
  • Ages > 18
  • All Genders

Study Summary

Aim of this study is to evaluate the correlation between the characteristics detected by the 7T MRI equipment and the histological composition of native explanted livers (group A), liver graft excluded for donation (group B) and surgical specimens of primary pancreatic tumour, which underwent pancreaticoduodenectomy (group C).

Eligibility Criteria

Inclusion

GROUP A of Native Liver Inclusion Criteria:

  • informed consent

  • full possession of one's faculties

  • patients who are going to undergo liver transplantation, independently from previoustherapy or from the primary disease they are affected by.

Exclusion

Exclusion Criteria:

  • patients affected by polycystic liver disease

  • excluded from liver transplantation. GROUP B of Excluded Grafts Inclusion Criteria:

  • liver grafts with histologically proven macrovescic steatosis, not fit fortransplantation Exclusion Criteria:

  • liver grafts histologically proven macrovescic steatosis fit for transplantation

  • liver grafts not fit for transplantation due to causes other than steatosis GROUP C of Focal Pancreatic Lesion Inclusion Criteria:

  • informed consent

  • full possession of one's faculties

  • pancreatic lesion assessed by CT examination and histologically proved, which arecandidates for pancreaticoduodenectomy or total pancreatectomy Exclusion Criteria:

  • excluded from surgery due to the severity of their condition.

Study Design

Total Participants: 30
Study Start date:
May 24, 2019
Estimated Completion Date:
December 31, 2020

Connect with a study center

  • Azienda Ospedaliero Universitaria Pisana

    Pisa, PI 56124
    Italy

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.