Evaluation of an Arterial Calcification Score as a Predictive Factor of Anastomotic Leakage in Right Colectomy

Last updated: July 26, 2023
Sponsor: Centre Hospitalier Departemental Vendee
Overall Status: Active - Recruiting

Phase

N/A

Condition

Scleroderma

Treatment

N/A

Clinical Study ID

NCT04002921
CHD 086-19
  • Ages > 18
  • All Genders

Study Summary

Anastomotic leakage is the major postoperative complication in right colectomy. Evaluation of calcification on coeliac trunk and mesenteric arteries on the preoperative CT scan could allow the identification of patient at-risk of postoperative complications.

A monocentric retrospective study performed at CHD Vendée concluded than a calcification score over or equal to 3 was associated with a higher risk of developping an anastomotic leakage.

The aim of this prospective multicentric study is to validate a calcification score based on preoperative CT scan analysis and focussing at coeliac trunk and mesenteric arteries.This study will involve patients operated on with a scheduled right colectomy.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age ≥ 18 years old
  • Scheduled right colectomy with restoration of digestive continuity
  • Patient who has had or will have a preoperative abdominal-pelvic CT scan with orwithout contrast injection
  • Patient with the ability to understand the protocol and agree to participate in thestudy.
  • Affiliated with a social security system

Exclusion

Exclusion Criteria:

  • Patient requiring a right colectomy or ileocaecal resection for chronic inflammatorybowel disease or on long-term corticosteroid therapy
  • Patient with a history of colic resection
  • Patient under guardianship, curatorship, or deprived of liberty
  • Pregnant, postpartum or breastfeeding women
  • Minor patients

Study Design

Total Participants: 1100
Study Start date:
September 24, 2019
Estimated Completion Date:
November 10, 2025

Connect with a study center

  • CHU Angers

    Angers,
    France

    Active - Recruiting

  • Hopital privé de Sévigné

    Cesson-Sévigné,
    France

    Active - Recruiting

  • CH de Challans

    Challans, 85300
    France

    Active - Recruiting

  • CH de Cholet 1 rue Marengo

    Cholet, 49300
    France

    Active - Recruiting

  • Centre Hospitalier de Fougères

    Fougères, 35300
    France

    Active - Recruiting

  • CHD Vendée

    La Roche sur Yon, 85925
    France

    Active - Recruiting

  • Centre Hospitalier de la Rochelle

    La Rochelle,
    France

    Active - Recruiting

  • Centre Hospitalier du Mans

    Le Mans,
    France

    Active - Recruiting

  • Clinique Mutualiste de la Porte de l'Orient

    Lorient, 56324
    France

    Active - Recruiting

  • CHU de Nantes

    Nantes, 44093
    France

    Active - Recruiting

  • Hopital privé des Cotes d'Armor

    Plérin,
    France

    Active - Recruiting

  • Clinique La Sagesse

    Rennes,
    France

    Active - Recruiting

  • Centre Hospitalier de Saint Brieuc

    Saint-Brieuc,
    France

    Active - Recruiting

  • Clinique Mutualiste de l'Estuaire

    Saint-Nazaire, 44600
    France

    Active - Recruiting

  • Centre Hospitalier Bretagne Atlantique

    Vannes, 56017
    France

    Active - Recruiting

  • Hôpital privé Océane

    Vannes,
    France

    Site Not Available

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