A Safety and Pharmacokinetics Study of IDP-122 Lotion in Pediatric Participants With Plaque Psoriasis

Inclusion Criteria:

• Is 6 to 16 years 11 months of age at time of informed consent/assent obtained.

• Verbal and written informed consent/assent obtained from the participant and/orparent or legal guardian.

• Has a clinical diagnosis of psoriasis at Screening and Baseline with anInvestigator's Global Assessment (IGA) score of 3 or 4. The face, scalp, axillae,and intertriginous areas are to be excluded in this assessment, if psoriasis ispresent.

• Has an area of plaque psoriasis appropriate for topical treatment that involves aBSA of at least 10% at Screening and Baseline. The face, scalp, axillae, andintertriginous areas are to be excluded in this calculation.

• Is willing and able to avoid prolonged exposure of the treatment area to ultravioletradiation (natural and artificial) for the duration of the study.

• Is in good general adrenal health, as determined by a 30-minute postcosyntropinstimulation serum cortisol level that is >18 μg/dL at the Screening visit.

• Females of childbearing potential and females who are pre-menses (9 years and older)must be willing to practice effective contraception for the duration of the study.

Exclusion Criteria:

• Has a history of adrenal disease.

• Presents with any concurrent skin condition that could interfere with the evaluationof the treatment areas, as determined by the Investigator.

• Is pregnant, nursing an infant, or planning a pregnancy during the study period.

• Has received treatment with any investigational drug or device within 60 days or 5drug half-lives (whichever is longer) prior to baseline or is concurrentlyparticipating in another clinical study with an investigational drug or device.

• Received treatment with a topical antipsoriatic drug product other thancorticosteroids within 14 days prior to the Baseline visit and/or treatmentcontaining corticosteroids within 28 days prior to the screening HPA axisstimulation test.

• Has a history of hypersensitivity or allergic reaction to any of the study drugconstituents.

• Is considered by the Investigator, for any other reason, to be an unsuitablecandidate for the study.