The Prevalence of a Low Ankle-Brachial Index in Acute Cerebral Ischemia.

Last updated: May 10, 2019
Sponsor: Jan Biziel University Hospital No 2 in Bydgoszcz
Overall Status: Active - Recruiting

Phase

N/A

Condition

Occlusions

Stroke

Cerebral Ischemia

Treatment

N/A

Clinical Study ID

NCT03948399
JBUH-ABI-CIE-2018
  • Ages 18-99
  • All Genders

Study Summary

Aim of the study is assessment the prevalence of the low ankle-brachial index (ABI) defined less than or equal 0.9 in patients with acute cerebral ischemic event (stroke or transient ischemic attack) and determinate the correlation between ABI and internal carotid artery stenosis (ICAS) in the acute cerebral ischemic patients.

The low ABI is a strong marker of generalized atherosclerosis. LEAD is a strong independent predictor for stroke.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Acute ischemic stroke or transient ischemic attack of anterior circulation

  • Consent of patient

Exclusion

Exclusion Criteria:

  • primary intracranial hemorrhage,

  • venous sinus thrombosis,

  • unconsciousness,

  • intubation,

  • inability to provide and write a consent application form.

Study Design

Total Participants: 200
Study Start date:
January 01, 2018
Estimated Completion Date:
December 31, 2020

Study Description

Aim of the study is assessment the prevalence of the low ankle-brachial index (ABI) defined less than or equal 0.9 in patients with acute cerebral ischemic event (stroke or transient ischemic attack) and determinate the correlation between ABI and internal carotid artery stenosis (ICAS) in the acute cerebral ischemic patients.

The ABI is a non-invasive tool useful for the diagnosis of LEAD. The low ABI is a strong marker of generalized atherosclerosis. LEAD is a strong independent predictor for stroke. Significant ICAS is prevalent among patients having LEAD. Acute ischemic stroke due to significant ICAS has poor prognosis.

Patients with LEAD may be a suitable subgroup for screening for ICAS using duplex scanning.

Estimating the relationship between cerebral ischemic event and the ABI value could help better guide preventive and risk reduction strategies.

Connect with a study center

  • Department of Neurosurgery and Neurology University Hospital nr 2 Collegium Medicum Nicolaus Copernicus University

    Bydgoszcz, 85-168
    Poland

    Active - Recruiting

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