Regional Anesthesia for Breast Surgery

Last updated: June 5, 2019
Sponsor: Arcispedale Santa Maria Nuova-IRCCS
Overall Status: Active - Recruiting

Phase

N/A

Condition

Breast Cancer

Cancer

Treatment

N/A

Clinical Study ID

NCT03941223
Breastblock
  • Ages > 18
  • Female

Study Summary

Patients scheduled for mastecotmy will be randomized to receive either an ultrasound-guided double space paravertebral block or a PECSII + parasternal block. In both groups, blocks will be performed with 20 ml of ropivacaine 0.75%, plus ropivacaine 0.375% 10 ml for parasternal block only.

Postoperative, all patients will receive a morphine PCA. They will follow at 6, 12, 24 months for persistent postoperative surgical pain (PPSP) and cancer recurrence.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients scheduled for radical mastectomy for cancer.

  • age > 18 y-o

  • Written informed consent

Exclusion

Exclusion Criteria:

  • Bilateral surgery

  • Opioids user

  • BMI > 35

  • Postoperative Intensive care

Study Design

Total Participants: 150
Study Start date:
May 29, 2019
Estimated Completion Date:
June 30, 2022

Study Description

Patients scheduled for mastecotmy with or without axillary dissection, will be randomized to receive preoperative either an ultrasound-guided double space paravertebral block or a PECSII

  • parasternal block. In both groups, blocks will be performed with 20 ml of ropivacaine 0.75%, plus ropivacaine 0.375% 10 ml for parasternal block only.

All the patients also received a general anesthesia induced by propofol and esmeron for endotracheal intubation and desflurane for maintaining.

Sensory block by ice and pinprick test application and maximum spread after 40' from LA injection will be registered.

Postoperative, all patients will receive a morphine PCA, ketorolac 30 mg/12h and paracetamol 1g each 8h.

Morphine consumption will be registered. Patients will follow at 6, 12, 24 months for persistent postoperative surgical pain (PPSP) and cancer recurrence.

Connect with a study center

  • AUSL IRCCS Reggio Emilia

    Reggio Emilia, 42120
    Italy

    Active - Recruiting

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