Metastatic Breast Cancer in Austria

Last updated: April 9, 2025
Sponsor: Arbeitsgemeinschaft medikamentoese Tumortherapie
Overall Status: Active - Recruiting

Phase

N/A

Condition

Cancer/tumors

Carcinoma

Breast Cancer

Treatment

N/A

Clinical Study ID

NCT03870620
AGMT_MBC-Registry
  • Ages > 18
  • All Genders

Study Summary

Breast cancer is the most common cancer among women worldwide. In Austria, this diagnosis is made more than 5000 times a year (STATISTICS AUSTRIA, Austrian Cancer Registry, as of 24.09.2012). Of these, already 5% to 10% have distant metastases at the time of initial diagnosis, and up to 30% of the node-negative tumours and up to 70% of the node-positive tumours metastasise at a later date. Metastatic breast cancer has not been systematically assessed in Austria to date. This medical registry of the AGMT is thus the first Austrian-wide standardised documentation of this disease. The aim of the registry is to answer both epidemiological and therapy-specific questions.

This registry is a prospective and retrospective, multicentre collection of data on patients with metastatic breast cancer in Austria. All tumour characteristics, medical histories and also treatment sequences are documented in anonymised form.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Histological evidence of breast cancer

  • Histological and/or radiological evidence of metastases

  • Metastasis within 10 years of registry initiation

  • Signed informed consent (if a patient has already died at the time of entry, theentry can be made without a declaration of consent)

Exclusion

Exclusion Criteria:

  • Due to the non-interventional design of the registry there are no specific exclusioncriteria.

Study Design

Total Participants: 5000
Study Start date:
June 15, 2015
Estimated Completion Date:
June 30, 2025

Study Description

The present AGMT registry will provide accurate documentation of initial disease progression and initial tumour characteristics in patients with metastatic breast cancer in Austria. The data collected will include: median age at metastasis, median disease-free survival (DFS) between initial diagnosis or first date of absence of disease and occurrence of metastasis, histological subtype of the primary tumour, initial TNM stage, grade and receptor status of the primary tumour, type and form of adjuvant therapy, pattern of metastasis and metastasis site. Characteristics that have a negative prognostic value are expected to be overrepresented in the metastatic patient group.

Also, this AGMT registry is intended to assess the distribution pattern of these metastatic stage subtypes in Austria. Additionally, their influence on treatment strategy and outcome is to be studied. Furthermore, the frequency and tumour characteristics of breast cancer in male patients will be assessed and the influence of gender on treatment strategies identified.

The AGMT breast cancer registry will conduct an exact analysis of survival data, thereby enabling accurate calculations of average survival duration in patients with metastatic breast cancer in Austria. Further parameters that reflect the quality or course of oncological treatment are the survival rates from the time of metastasis development at 1, 2 and 5 years after diagnosis.

This AGMT registry is intended to investigate the response to various therapies in a real life population in relation to previous treatments, concomitant diseases and breast cancer subtype. The aim is to assess which therapies are used at which time point and on which disease subtype they depend.

Connect with a study center

  • Kepler Universitätsklinikum; Univ.-Klinik für Hämatologie und Internistische Onkologie

    Linz, Oberösterreich 4020
    Austria

    Active - Recruiting

  • Ordensklinikum Linz GmbH - Barmherzige Schwestern; Interne I: Medizinische Onkologie und Hämatologie

    Linz, Oberösterreich 4020
    Austria

    Active - Recruiting

  • Pyhrn-Eisenwurzen Klinikum Steyr; Innere Medizin II: Onkologie, Gastroenterologie, Angiologie

    Steyr, Oberösterreich 4400
    Austria

    Active - Recruiting

  • Klinikum Wels-Grieskirchen GmbH; Abteilung für Innere Medizin IV

    Wels, Oberösterreich 4600
    Austria

    Active - Recruiting

  • Steiermärkische Krankenanstalten- gesellschaft m. b. H. LKH-Univ. Klinikum Graz; Universitätsklinik für Innere Medizin; Klinische Abteilung für Onkologie

    Graz, Steiermark 8036
    Austria

    Active - Recruiting

  • Landeskrankenhaus - Universitätskliniken Innsbruck; Universitätsklinik für Frauenheilkunde Innsbruck

    Innsbruck, Tirol 6020
    Austria

    Active - Recruiting

  • BKH Kufstein; Innere Medizin: Interne II und onk. Tagesklinik

    Kufstein, Tirol 6330
    Austria

    Active - Recruiting

  • LKH Feldkirch; Innere Medizin II/ Interne E (Hämatologie und Onkologie)

    Feldkirch, Vorarlberg 6800
    Austria

    Active - Recruiting

  • Krankenhaus St. Josef Braunau; Inneren Medizin 2

    Braunau am Inn, 5280
    Austria

    Active - Recruiting

  • Krankenhaus der Stadt Dornbirn; Brustgesundheitszentrum Dornbirn

    Dornbirn, 6850
    Austria

    Active - Recruiting

  • Steiermärkische Krankenanstalten- gesellschaft m.b.H. LKH Hochsteiermark; Department für Hämato-Onkologie

    Leoben, 8700
    Austria

    Active - Recruiting

  • Landeskrankenhaus Salzburg Universitätsklinikum der Paracelsus Medizinischen Privatuniversität; Universitätsklinik für Innere Medizin III Salzburg

    Salzburg, 5020
    Austria

    Active - Recruiting

  • Universitätsklinikum St. Pölten; Abteilung für Innere Medizin 1

    St. Pölten, 3100
    Austria

    Active - Recruiting

  • Klinik Ottakring; 1. Med. Abteilung, Zentrum f. Onkologie, Hämatologie und Palliativmedizin

    Vienna, 1160
    Austria

    Active - Recruiting

  • AKH Wien; Universitätsklinik für Frauenheilkunde: Klin. Abt. f. Allg. Gynäkologie und gynäkologische Onkologie

    Wien, 1090
    Austria

    Active - Recruiting

  • UK AKH Wien: Universitätsklinik für Innere Medizin I: Klinische Abteilung für Onkologie

    Wien, 1090
    Austria

    Active - Recruiting

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