Infectious Agents Exposure : Archiving in Dental Plaque

Last updated: March 5, 2019
Sponsor: University Hospital, Brest
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT03864952
29BRC18.0131 (DIAS study)
  • Ages > 18
  • All Genders

Study Summary

We are studying the possibility of using dental calculus as a reservoir for the genes of an infectious agent that has infected the patient in previous months; as it is done to highlight climate change in ice samples.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • three months before, having been infected with a documented pathogen

  • this infection must have been clinically obvious

  • the patient must have dental calculus

Exclusion

Exclusion Criteria:

  • to be under 18 years old

  • to be incapable to consenting

  • a tartar removal since the infection

Study Design

Total Participants: 15
Study Start date:
March 04, 2019
Estimated Completion Date:
September 04, 2019

Study Description

From a sample of people who have had a microbiologically well-documented infection, we will study the possibility after genomic amplification to find, three to 12 months after genetic sequences of the infectious agent in the dental calculus of the person. The people will be recruited according to a large panel of infectious agent (gram + and gram bacterium, mycobacteria, parasite, fungus, DNA, RNA or retrovirus) and, of course, the presence of dental calculus.

Connect with a study center

  • CHRU de Brest

    Brest, 29609
    France

    Active - Recruiting

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