Early Diagnosis for Ocular Ischemia Syndrome Using Arterial Spin Labeling Magnetic Resonance Imaging Technique

Last updated: March 12, 2019
Sponsor: Beijing Friendship Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Occlusions

Treatment

N/A

Clinical Study ID

NCT03863171
2018-P2-185-02
  • Ages 50-80
  • All Genders

Study Summary

  1. To evaluate ocular blood perfusion status and the possibility of craniocerebral vascular lesions of patients with ocular ischemia syndrome (OIS) using arterial spin labeling (ASL) magnetic resonance imaging technique.

  2. To evaluate the specificity, sensitivity and accuracy of arterial spin labeling (ASL) magnetic resonance imaging technique in OIS diagnosis, compared with the traditional routine examination method.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Ocular ischemia syndrome group: Patients diagnosed with ocular ischemia syndrome;

  • Age-related macular degeneration group (Control group): Patients diagnosed withage-related macular degeneration;

  • Age: 50-80 years;

  • Sex: all;

  • Patients signed written informed consent.

Exclusion

Exclusion Criteria:

  • Fundus fluorescein angiography (FFA) clear images cannot be obtained due to refractivemedia problems(such as corneal leukoplakia, severe cataract, vitreous hemorrhage,etc.) ;

  • Patients with contraindications for FFA;

  • Patients was unable to perform magnetic resonance rmaging (MRI) test;

  • Patients with history of bleeding and cerebral infarction;

  • Patients with a history of surgery within 3 months;

  • Patients who had participated in other clinical trials within 3 months;

  • Patients who disagree and refuse to participate in the trial.

Study Design

Total Participants: 190
Study Start date:
March 01, 2019
Estimated Completion Date:
March 01, 2021

Connect with a study center

  • Beijing Friendship Hospital

    Beijing, Beijing
    China

    Active - Recruiting

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