Phase
Condition
Lung Disease
Pleural Effusion
Treatment
KM
KRP-NI + KM
Clinical Study ID
Ages > 18 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
≥ eighteen years old
to be hospitalized for an infectious pleural outpouring
to have a liquid pleural outpouring diagnosed by echography or to scan thoracic
presence of a Exudate according to the criteria of Light, to have at least criteria:
The ratio of pleural fluid protein to serum protein is greater than 0.5
The ratio of pleural fluid Lactate dehydrogenase (LDH) and serum LDH is greaterthan 0.6
The rate of pleural fluid LDH is > 2/3 upper limit of normal serum LDH of thelaboratory concerned
presence of at least two of the following criteria:
fever higher or equal 38°C (100.4°F)
thoracic pain
purulent sputum
purulent pleural effusion at the time of the exploring pleural puncture
hearth of crackling to the sounding
Inflammatory syndrome (CRP>15 mg/l and/or White blood cell >10 000 /mm3)
no known radiological hearth before
Having undergone an evacuation gesture going back to less forty-eight hours:evacuation pleural puncture or repeated pleural punctures or pleural drainageallowing the evacuation of at least 100cc of pleural fluid
Informed and having given its free, lit and express assent
Patients with affiliation to the social security system
Exclusion
Exclusion Criteria:
Patient having undergone a thoracotomy or thoracoscopy in the six previous months
Patient having a pneumothorax
Patient reached of a tuberculosis
Patient unable to carry out a measurement of the vital capacity by portablespirometer at the inclusion
Pregnant woman or nursing
Patient having a life expectancy lower than three months
Proven or suspected pleural neoplasia disease
Patient hemodynamically unstable
Patient having a respiratory insufficiency requiring the introduction of anartificial ventilation
Patient carrying a chronic respiratory insufficiency under non-invasive ventilationwith the long course
Patient unable to carry out the exercises of physiotherapy (problem of communicationand/or comprehension and/or physical inaptitude)
Patient transplanted of a solid body, allograft or autograft of hematopoietic stemcells
Patient with a seropositivity for the known HIV and cluster of differentiation 4 (CD4) <250/mm3
Study Design
Study Description
Connect with a study center
Centre Hospitalier Universitaire Angers
Angers, 49000
FranceSite Not Available
Hôpital Victor Dupuy
Argenteuil, 95100
FranceSite Not Available
Centre Hospitalier Henri Duffaut - Avignon
Avignon, 84 000
FranceSite Not Available
Hôpital de la Cavale Blanche
Brest, 29200
FranceSite Not Available
Centre Hospitalier de Cholet
Cholet, 49 300
FranceSite Not Available
Centre Hospitalier Intercommunal - Créteil
Créteil, 94 000
FranceSite Not Available
Centre Hospitalier de Dunkerque
Dunkerque, 59240
FranceSite Not Available
Centre Hospitalier Universitaire de Grenoble
Grenoble, 38700
FranceSite Not Available
Groupe Hospitalier de la Rochelle
La Rochelle, 17000
FranceSite Not Available
Hôpital Dupuytren
Limoges, 87000
FranceSite Not Available
Centre Hospitalier de Mont-de-Marsan
Mont-de-Marsan, 40024
FranceSite Not Available
Centre Hospitalier Régional d'Orléans
Orléans, 45067
FranceSite Not Available
Hôpital Bichat - Claude Bernard
Paris, 75018
FranceSite Not Available
Centre Hospitalier René Dubos
Pontoise, 95303
FranceSite Not Available

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