Usefulness of Capillary Refill Time and Skin Mottling Score to Predict Intensive Care Unit Admission

Last updated: February 4, 2019
Sponsor: Hôpital Necker-Enfants Malades
Overall Status: Active - Recruiting

Phase

N/A

Condition

Low Blood Pressure (Hypotension)

Treatment

N/A

Clinical Study ID

NCT03831022
2018-A02588-47
  • Ages > 18
  • All Genders

Study Summary

In the emergency department (ED), the severity assessment of shock is a fundamental step prior to the admission in intensive care unit (ICU). As biomarkers are time consuming to evaluate severity of the micro and macro-circulation alteration, capillary refill time and skin mottling score are 2 simples, available clinical criteria validated to predict mortality in the ICU.

The aim of this study is to provide clinical evidence that capillary refill time and skin mottling score assessed in the ED also predict ICU admission of patients with septic or haemorrhagic shock.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Age > 18 years

  2. Skin mottling score> 2 and/or capillary refill time > 3secondes associated with atleast one of the followings measured at the ED admission by the nurse in charge of thepatient:

  3. Systolic blood pressure < 90mmHg or blood pressure decrease of 30% at least forpatients with high blood pressure history

  4. Heart rate > 120 beats per minute

  5. Respiratory rate > 22 movements per minute

  6. Glasgow coma scale < 13.

Exclusion

Exclusion Criteria:

  1. Age < 18 years

  2. Pregnancy

  3. Serious co morbid conditions with a not to be reanimated status known at the EDadmission

  4. Patients with guardianship or curator

Study Design

Total Participants: 1500
Study Start date:
December 17, 2018
Estimated Completion Date:
December 17, 2020

Study Description

This trial is an observational, non-randomized controlled study. A total of 1500 patients admitted to the ED for a septic or hemorrhagic shock will be followed.

The primary outcome is the admission to the ICU.

The study will not impact the treatments provided to each patient. Capillary refill time and skin mottling score will not be taken into account to decide patient's treatments and/or ICU admission. Patients will be followed during their hospital stay in order to precise their destination after ED (home, ICU, ward) and 28- and 90-days mortality after hospital admission.

Connect with a study center

  • Necker enfants malades Hospital

    Paris, Ile De France 75015
    France

    Active - Recruiting

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