Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) with a Transitional Pain Service

Last updated: March 17, 2025
Sponsor: Hospital for Special Surgery, New York
Overall Status: Active - Recruiting

Phase

N/A

Condition

Anesthesia

Treatment

Continuous Adductor Canal Catheter (ACC)

Adductor Canal block with sham catheter

Clinical Study ID

NCT03747146
2017-1858
  • Ages 18-65
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

A comparison of two anesthetic techniques for total knee replacements: (1) Peri-Articular Injection (PAI), local infiltration between the popliteal artery and capsule of the knee block (IPACK) and single-shot adductor canal block (ACB) vs. (2) PAI, IPACK and continuous adductor canal block catheter (ACC).

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients with osteoarthritis scheduled for a primary total knee arthroplasty with aparticipating surgeon

  • Planned use of regional anesthesia

  • Ability to follow study protocol

  • English speaking (secondary outcomes include questionnaires validated in Englishonly)

  • Lives within one hour of the hospital

  • Has a smart phone

Exclusion

Exclusion Criteria:

  • Hepatic or renal insufficiency

  • Younger than 18 years old or older than 65 years ol

  • Patients undergoing general anesthesia

  • Allergy or intolerance to one of the study medications

  • BMI >40

  • Diabetes

  • American Society of Anesthesiologists (ASA) status III or IV

  • Chronic gabapentin/pregabalin use (regular use for longer than 3 months)

  • Patients with chronic pain (from a referral to chronic pain service) or a paincatastrophizing scale (PCS >30)

  • Patients with severe valgus deformity or flexion contracture

  • Patients unable to follow home catheter instructions and unwilling to go home withan infusing catheter

  • Patients who have no home caregivers in the event that a catheter is to be sent homewith the patient

  • Patients with planned stay at rehab facility (to avoid medical device being tamperedwith at the rehab facility)

  • Non-English speakers (secondary outcomes include questionnaires validated in Englishonly)

Study Design

Total Participants: 94
Treatment Group(s): 2
Primary Treatment: Continuous Adductor Canal Catheter (ACC)
Phase:
Study Start date:
November 16, 2018
Estimated Completion Date:
December 31, 2025

Study Description

Patients will be randomized to one of two groups: one group will receive a PAI, IPACK and single-shot adductor canal block; one group will receive PAI, IPACK and continuous adductor canal block catheter.

Connect with a study center

  • Hospital for Special Surgery

    New York, New York 10023
    United States

    Active - Recruiting

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