KRT-232 Versus Best Available Therapy for the Treatment of Subjects With Myelofibrosis Who Are Relapsed or Refractory to JAK Inhibitor Treatment

Last updated: April 26, 2023
Sponsor: Kartos Therapeutics, Inc.
Overall Status: Active - Recruiting

Phase

2/3

Condition

Red Blood Cell Disorders

Leukemia (Pediatric)

Myelofibrosis

Treatment

N/A

Clinical Study ID

NCT03662126
KRT-232-101
  • Ages > 18
  • All Genders

Study Summary

This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2, for the treatment of patients with myelofibrosis (MF) who no longer benefit from treatment with a JAK inhibitor. Inhibition of MDM2 is a novel mechanism of action in MF.

This study will be conducted in 2 phases. Phase 2 will determine the KRT-232 recommended dose and dosing schedule; Phase 3 will test KRT-232 vs Best Available Therapy (BAT). Patients in the Phase 3 part of the study will be randomized 2:1 to receive either KRT-232 (Arm 1) or BAT (Arm 2). The BAT administered will be determined by the treating physician, with the option to "cross-over" to KRT-232 treatment after 6 months of BAT or if the disease worsens at any time.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Confirmed diagnosis of PMF, post-PV MF or post-ET MF (WHO)
  • High, intermediate-2, or intermediate-1 risk Dynamic International Prognostic System (DIPSS)
  • Failure of prior treatment with JAK inhibitor
  • ECOG ≤ 2

Exclusion

Exclusion Criteria:

  • Prior splenectomy
  • Splenic irradiation within 3 months prior to randomization
  • History of major hemorrhage or intracranial hemorrhage within 6 months prior torandomization
  • History of stroke, reversible ischemic neurological defect or transient ischemicattack within 6 months prior to randomization
  • Prior MDM2 inhibitor therapy or p53-directed therapy
  • Prior allogeneic stem-cell transplant or plans for allogeneic stem cell transplant
  • History of major organ transplant
  • Grade 2 or higher QTc prolongation (> 480 milliseconds per NCI-CTCAE criteria, version 5.0)

Study Design

Total Participants: 385
Study Start date:
January 15, 2019
Estimated Completion Date:
December 31, 2025

Connect with a study center

  • University of the Philippines - Philippine General Hospital

    Manila, 1000
    Philippines

    Active - Recruiting

    0.87 miles

  • Perpetual Succour Hospital - Hemat/Transfusion Med

    Cebu City, 6000
    Philippines

    Active - Recruiting

    349.83 miles

  • Kaohsiung Medical University - Chung-Ho Memorial Hospital

    Kaohsiung, 807
    Taiwan

    Active - Recruiting

    555.25 miles

  • China Medical University Hospital

    Taichung, 40447
    Taiwan

    Active - Recruiting

    659.35 miles

  • Queen Mary Hospital

    Hong Kong, 150001
    Hong Kong

    Active - Recruiting

    692.85 miles

  • Srinagarind Hospital (KhonKaen University)

    Khon Kaen, 40002
    Thailand

    Active - Recruiting

    1,214.62 miles

  • Thammasat University Hospital

    Khlong Luang, 12120
    Thailand

    Active - Recruiting

    1,361.63 miles

  • Ramathibodi Hospital - Mahidol University - Hematology

    Bangkok, 10400
    Thailand

    Active - Recruiting

    1,373.47 miles

  • Siriraj Hospital

    Bangkok, 10700
    Thailand

    Active - Recruiting

    1,373.47 miles

  • Songklanagarind Hospital

    Songkhla, 90110
    Thailand

    Active - Recruiting

    1,473.45 miles

  • Inje University Busan Paik Hospital

    Busan, 47392
    Korea, Republic of

    Active - Recruiting

    1,507.68 miles

  • Keimyung University Dongsan Medical Center

    Daegu, 42601
    Korea, Republic of

    Active - Recruiting

    1,543.05 miles

  • Kyungpook National University Hospital

    Daegu, 41944
    Korea, Republic of

    Active - Recruiting

    1,543.05 miles

  • Yeungnam University Medical Center

    Daegu, 42415
    Korea, Republic of

    Active - Recruiting

    1,543.05 miles

  • Samsung Medical Center

    Seoul, 06351
    Korea, Republic of

    Active - Recruiting

    1,628.15 miles

  • Seoul National University Hospital

    Seoul, 03080
    Korea, Republic of

    Active - Recruiting

    1,628.15 miles

  • The Catholic University of Korea, Seoul St. Mary's Hospital

    Seoul, 6591
    Korea, Republic of

    Active - Recruiting

    1,628.15 miles

  • Royal Adelaide Hospital

    Adelaide,
    Australia

    Active - Recruiting

    3,611.93 miles

  • Clinical oncological dispensary

    Omsk, 644013
    Russian Federation

    Site Not Available

    3,763.85 miles

  • The Alfred Hospital

    Melbourne,
    Australia

    Active - Recruiting

    3,941.55 miles

  • Oncologic dispensary of Komi Republic

    Syktyvkar, 167904
    Russian Federation

    Site Not Available

    4,684.72 miles

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    Malatya, 44280
    Turkey

    Active - Recruiting

    5,204.3 miles

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    Gaziantep, 27100
    Turkey

    Active - Recruiting

    5,267.04 miles

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    Samsun, 55280
    Turkey

    Active - Recruiting

    5,282.52 miles

  • Mersin University Medical Faculty

    Mersin, 33110
    Turkey

    Active - Recruiting

    5,419.67 miles

  • Ha'Emek Medical Center

    Afula, 1834111
    Israel

    Active - Recruiting

    5,433.04 miles

  • Carmel MC

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    Israel

    Active - Recruiting

    5,446.95 miles

  • Rambam Medical Centre

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    Israel

    Active - Recruiting

    5,446.95 miles

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    Israel

    Active - Recruiting

    5,447.94 miles

  • Gazi University Medical Faculty

    Ankara, 06500
    Turkey

    Active - Recruiting

    5,477.59 miles

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    Ankara, 06500
    Turkey

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    5,477.59 miles

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    Ashdod,
    Israel

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    5,479.8 miles

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    Kaunas, LT-50161
    Lithuania

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    5,672.03 miles

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    Turkey

    Active - Recruiting

    5,705.91 miles

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    Romania

    Active - Recruiting

    5,751.05 miles

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    Romania

    Active - Recruiting

    5,753.58 miles

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    Poland

    Site Not Available

    5,789.89 miles

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    Olsztyn,
    Poland

    Active - Recruiting

    5,824.99 miles

  • Institutul Oncologic "Prof. Dr. Ion Chiricuta"

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    Romania

    Active - Recruiting

    5,828.32 miles

  • University Multiprofile Hospital for Active Treatment Dr. Georgi Stranski, Pleven

    Pleven,
    Bulgaria

    Active - Recruiting

    5,840.17 miles

  • Szpital Specjalistyczny w Brzozowie Podkarpacki Ośrodek Onkologiczny im. Ks. B. Markiewicza

    Brzozow, Podkarpackie 36-200
    Poland

    Site Not Available

    5,842.56 miles

  • University Multiprofile Hospital for Active Treatment Sveti Georgi, Plovdiv

    Plovdiv,
    Bulgaria

    Active - Recruiting

    5,856.26 miles

  • Spitalul Clinic Municipal Filantropia Craiova

    Craiova, 200143
    Romania

    Active - Recruiting

    5,862.05 miles

  • Debreceni Egyetem Orvos es Egeszsegtudomanyi Centrum

    Debrecen, 4032
    Hungary

    Completed

    5,901.57 miles

  • University Multiprofile Hospital for Active Treatment Saint Ivan Rilski, Sofia

    Sofia,
    Bulgaria

    Active - Recruiting

    5,915.96 miles

  • Military Medical Academy, Multiprofile for active treatment, Sofia

    Sofia, 1606
    Bulgaria

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    5,915.96 miles

  • University Multiprofile Hospital for Active Treatment Alexandrovska, Sofia

    Sofia,
    Bulgaria

    Site Not Available

    5,915.96 miles

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    Bulgaria

    Active - Recruiting

    5,915.96 miles

  • Specialized Hospital for Active Therapy of Hematological Disorders

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    Bulgaria

    Active - Recruiting

    5,915.96 miles

  • Szpital Uniwersytecki nr 2 im dr. Jana Biziela

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    Poland

    Active - Recruiting

    5,936.0 miles

  • Szpital Wojewódzki w Opolu

    Opole, 45-061
    Poland

    Active - Recruiting

    5,994.3 miles

  • Szegedi Tudományegyetem

    Szeged, 6725
    Hungary

    Active - Recruiting

    5,995.08 miles

  • Semmelweis Egyetem

    Budapest, 1083
    Hungary

    Site Not Available

    6,017.45 miles

  • Dél-pesti Centrumkórház - Országos Hematológiai és Infektológiai Intézet

    Budapest,
    Hungary

    Active - Recruiting

    6,017.45 miles

  • Charité Universitätsmedizin Berlin

    Berlin, 13353
    Germany

    Active - Recruiting

    6,130.05 miles

  • Markusovszky Egyetemi Oktatókórház

    Szombathely, Vas H-9700
    Hungary

    Active - Recruiting

    6,130.57 miles

  • Clinical Hospital Centre Osijek

    Zagreb, 10000
    Croatia

    Active - Recruiting

    6,193.43 miles

  • KB Sestre Milosrdnice

    Zagreb, 10000
    Croatia

    Active - Recruiting

    6,193.43 miles

  • UKE - Universitätsklinikum Hamburg-Eppendorf

    Hamburg, 20251
    Germany

    Active - Recruiting

    6,230.3 miles

  • General Hospital Sibenik

    Sibenik, 22000
    Croatia

    Active - Recruiting

    6,248.88 miles

  • AOU Ospedali Riuniti Umberto I G.M. Lancisi G. Salesi

    Ancona, 60123
    Italy

    Active - Recruiting

    6,362.1 miles

  • Azienda Ospedaliera Ospedali Riuniti Marche Nord - Pesaro

    Pesaro, 61121
    Italy

    Active - Recruiting

    6,382.47 miles

  • Universitätsmedizin der Johannes Gutenberg Universität Mainz

    Mainz,
    Germany

    Site Not Available

    6,405.04 miles

  • Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST IRCCS

    Meldola,
    Italy

    Active - Recruiting

    6,415.34 miles

  • A.O.di Bologna Policl.S.Orsola

    Bologna, 41038
    Italy

    Active - Recruiting

    6,437.24 miles

  • Azienda Ospedaliero Universitaria Policlinico - Vittorio Emanuele

    Catania, 95123
    Italy

    Active - Recruiting

    6,442.95 miles

  • AO Spedali Civili di Brescia

    Brescia, 25123
    Italy

    Active - Recruiting

    6,457.13 miles

  • University of Florence

    Florence,
    Italy

    Site Not Available

    6,461.65 miles

  • Arcispedale S. Maria Nuova, AO di Reggio Emilia

    Reggio Emilia, 42123
    Italy

    Active - Recruiting

    6,463.16 miles

  • AOU Maggiore della Carità

    Novara, 28100
    Italy

    Active - Recruiting

    6,529.84 miles

  • PO Civile SS.Antonio e Biagio

    Alessandria, 15121
    Italy

    Active - Recruiting

    6,546.06 miles

  • Hôpital Claude Huriez

    Lille, 59037
    France

    Site Not Available

    6,585.12 miles

  • NHS Greater Glasgow and Clyde

    Glasgow,
    United Kingdom

    Site Not Available

    6,633.01 miles

  • Centre Hospitalier Universitaire D'Amiens (Hopital Sud) - Hématologie Clinique

    Amiens, 80054
    France

    Active - Recruiting

    6,640.1 miles

  • Guy's and Saint Thomas' NHS Foundation Trust

    London, SE1 9RT
    United Kingdom

    Site Not Available

    6,669.88 miles

  • Hôpital Saint-Louis

    Paris, 75010
    France

    Active - Recruiting

    6,675.23 miles

  • Hopital Paul Brousse - Aphp Hôpitaux Universitaires Paris Su

    Villejuif, 94800
    France

    Active - Recruiting

    6,677.1 miles

  • University Hospitals Birmingham NHS Foundation Trust

    Birmingham,
    United Kingdom

    Site Not Available

    6,694.42 miles

  • Oregon Health and Science University

    Portland, Oregon 97239
    United States

    Completed

    6,698.3 miles

  • Oxford University Hospitals NHS Foundation Trust

    Oxford,
    United Kingdom

    Site Not Available

    6,700.63 miles

  • Centre Hospitalier Universitaire of Caen Normandie - Côte de Nacre

    Caen, 14000
    France

    Site Not Available

    6,767.49 miles

  • Centre Hospitalier Le Mans

    Le Mans,
    France

    Active - Recruiting

    6,790.03 miles

  • Tom Baker Cancer Center

    Calgary, Alberta T2N4N2
    Canada

    Site Not Available

    6,823.61 miles

  • Centre Hospitalier Universitaire de Poitiers

    Poitiers,
    France

    Active - Recruiting

    6,837.75 miles

  • Center Hospitalier Universitaire d'Angers

    Angers, 49933 Cedex 09
    France

    Active - Recruiting

    6,839.48 miles

  • Institut Universitaire du Cancer de Toulouse Oncopole

    Toulouse, 31059
    France

    Active - Recruiting

    6,900.76 miles

  • Institut Bergonié

    Bordeaux, 33076
    France

    Site Not Available

    6,940.17 miles

  • Hospital Universitario Vall d'Hebrón

    Barcelona, 08035
    Spain

    Active - Recruiting

    6,947.42 miles

  • Hospital de La Santa Creu i Sant Pau

    Barcelona, 8041
    Spain

    Active - Recruiting

    6,947.42 miles

  • Stanford Cancer Center - Palo Alto

    Stanford, California 94305
    United States

    Site Not Available

    6,990.33 miles

  • C.H de la Côte Basque - Serviv

    Bayonne, 64100
    France

    Active - Recruiting

    7,028.63 miles

  • Complejo Hospitalario de Navarra - H. de Navarra, Hematología C/ de Irunlarrea, 3, Pamplona

    Pamplona, 31008
    Spain

    Active - Recruiting

    7,061.46 miles

  • H. Quirón Zaragoza

    Zaragoza, 50012
    Spain

    Active - Recruiting

    7,072.64 miles

  • Hospital Universitario Doctor Peset

    Valencia, 46017
    Spain

    Active - Recruiting

    7,130.69 miles

  • Hospital Universitario Ramón Y Cajal

    Madrid, 28034
    Spain

    Site Not Available

    7,242.18 miles

  • Hospital Universitario Puerta de Hierro - Majadahonda

    Majadahonda, Madrid 28222
    Spain

    Site Not Available

    7,247.28 miles

  • University of Southern California Norris Comprehensive Cancer Center

    Los Angeles, California 90033
    United States

    Site Not Available

    7,297.78 miles

  • Hospital Universitario de Salamanca

    Salamanca, 37007
    Spain

    Active - Recruiting

    7,303.94 miles

  • Innovative Clinical Research Institute

    Whittier, California 90603
    United States

    Completed

    7,312.33 miles

  • University of California San Diego Moores Cancer Center

    La Jolla, California 92093
    United States

    Site Not Available

    7,387.18 miles

  • Hospital de Braga

    Braga, 4710-243
    Portugal

    Active - Recruiting

    7,393.08 miles

  • H. Infante Dom Pedro. Centro Hospitalar do Baixo Vouga

    Aveiro, 3814-501
    Portugal

    Active - Recruiting

    7,441.93 miles

  • Instituto Português de Oncologia de Coimbra

    Coimbra, 3000-075
    Portugal

    Active - Recruiting

    7,450.94 miles

  • Champalimaud Cancer Center

    Lisbon, 1400-038
    Portugal

    Active - Recruiting

    7,544.77 miles

  • Avera Cancer Institute

    Sioux Falls, South Dakota 57105
    United States

    Active - Recruiting

    7,767.08 miles

  • Health Partners Institute

    Saint Paul, Minnesota 55101
    United States

    Site Not Available

    7,800.25 miles

  • Medical College of Wisconsin - Froedtert Hospital

    Milwaukee, Wisconsin 53226
    United States

    Active - Recruiting

    8,048.95 miles

  • University of Illinois at Chicago

    Chicago, Illinois 60612
    United States

    Active - Recruiting

    8,127.2 miles

  • Northwestern University Feinberg School of Medicine

    Chicago, Illinois 60611
    United States

    Completed

    8,128.2 miles

  • Princess Margaret Cancer Center

    Toronto, Ontario M5G 2M9
    Canada

    Site Not Available

    8,204.96 miles

  • Washington University School of Medicine

    Saint Louis, Missouri 63110
    United States

    Active - Recruiting

    8,240.23 miles

  • Gabrail Cancer Center

    Canton, Ohio 44718
    United States

    Active - Recruiting

    8,344.22 miles

  • The Ohio State University Comprehensive Cancer Center

    Columbus, Ohio 43210
    United States

    Completed

    8,359.79 miles

  • Dana-Farber Cancer Institute

    Boston, Massachusetts 02215
    United States

    Site Not Available

    8,426.91 miles

  • Yale University

    New Haven, Connecticut 06519
    United States

    Site Not Available

    8,472.75 miles

  • Summit Medical Group

    Florham Park, New Jersey 07932
    United States

    Site Not Available

    8,484.98 miles

  • Vanderbilt University Medical Center

    Nashville, Tennessee 37203
    United States

    Active - Recruiting

    8,488.51 miles

  • Mt. Sinai

    New York, New York 10029
    United States

    Active - Recruiting

    8,490.97 miles

  • New York Presbyterian/Weill Cornell Medical Center

    New York, New York 10021
    United States

    Site Not Available

    8,492.31 miles

  • Brookdale University Hospital and Medical Center

    Brooklyn, New York 11212
    United States

    Active - Recruiting

    8,500.07 miles

  • Instituto Mexicano del Seguro Social

    Monterrey, 64180
    Mexico

    Active - Recruiting

    8,505.34 miles

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas 77030
    United States

    Active - Recruiting

    8,531.34 miles

  • Sociedad de Metabolismo y Corazón S.C. - Oncology

    Veracruz, 91910
    Mexico

    Active - Recruiting

    8,996.56 miles

  • Oaxaca Site Management Organization OSMO

    Oaxaca, 6800
    Mexico

    Active - Recruiting

    9,060.32 miles

  • University Cancer Institute

    Boynton Beach, Florida 33426
    United States

    Site Not Available

    9,261.28 miles

  • Instituto Medico Alexander Fleming

    Buenos Aires,
    Argentina

    Active - Recruiting

    11,054.2 miles

  • Sanatorio de la Mujer

    Rosario, Santa Fe S2000ORE
    Argentina

    Active - Recruiting

    11,164.11 miles

  • Associação Educadora São Carlos AESC - Hospital Mãe de Deus - Centro de Pesquisa

    Porto Alegre, 90880-480
    Brazil

    Active - Recruiting

    11,260.87 miles

  • Hospital de Clinicas de Porto Alegre - Centro de Pesquisa Clinica

    Porto Alegre, 90035-903
    Brazil

    Active - Recruiting

    11,260.87 miles

  • Instituto de Ensino e Pesquisa São Lucas

    Sao Paulo, 01236-030
    Brazil

    Active - Recruiting

    11,419.66 miles

  • Hospital A C Camargo - Fundacao Antonio Prudente

    Sao Paulo, 01509-900
    Brazil

    Active - Recruiting

    11,419.66 miles

  • Hospital das Clínicas da Universidade de São Paulo

    Sao Paulo, 05403-000
    Brazil

    Active - Recruiting

    11,419.66 miles

  • UNICAMP - Universidade Estadual de Campinas Hemocentro

    Campinas, São Paulo 13083
    Brazil

    Active - Recruiting

    11,467.32 miles

  • Fundacao Doutor Amaral Carvalho

    Jau, 17210-120
    Brazil

    Active - Recruiting

    11,569.67 miles

  • Gemeinschaftspraxis Haematologie - Onkologie - Hauptstelle

    Dresden, Sachsen 01307
    Germany

    Active - Recruiting

  • Stauferklinikum Schwäbisch Gmünd

    Mutlangen, 73557
    Germany

    Active - Recruiting

  • AHEPA General Hospital of Thessaloniki

    Thessaloníki, 54636
    Greece

    Active - Recruiting

  • Hematology Institute

    Kfar Saba, 44281
    Israel

    Active - Recruiting

  • Western Galilee Hospital - Nahariya

    Nahariya, 22100
    Israel

    Active - Recruiting

  • A.O. Citta della Salute e della Scienza di Torino

    Torino, 10126
    Italy

    Active - Recruiting

  • Samodzielny Publiczny Zakład Opieki Zdrowotnej Zespół Szpitali Miejskich

    Chorzów, Slaskie 41-500
    Poland

    Active - Recruiting

  • Wojewodzki Szpital Specjalistyczny im. Janusza Korczaka w Slupsku Sp. z o.o.

    Słupsk, 76-200
    Poland

    Active - Recruiting

  • Spitalul Clinic Municipal de Urgenta Timisoara

    Timişoara, 300079
    Romania

    Active - Recruiting

  • Sakarya Research and Training Hospital

    Adapazarı, 54100
    Turkey

    Active - Recruiting

  • Icon Cancer Center

    South Brisbane,
    Australia

    Active - Recruiting

  • Hospital das Clínicas UFG

    Goiânia, 74605
    Brazil

    Active - Recruiting

  • Instituto D'or de Pesquisa e Ensino

    São Paulo, 04502-001
    Brazil

    Active - Recruiting

  • Centre Hospitalier Regional Universitaire Brest Hopital Morvan

    Brest Cedex, 29609
    France

    Active - Recruiting

  • Universitätsklinikum Halle

    Halle, Sachsen-Anhalt 06120
    Germany

    Active - Recruiting

  • Tel Aviv Sourasky Medical Center - Oncology

    Tel Aviv, 6423906
    Israel

    Active - Recruiting

  • H. São Francisco Xavier-Centro Hospitalar Lisboa Ocidental

    Lisboa, 1495-005
    Portugal

    Active - Recruiting

  • Centre Hospitalier Universitaire de Nîmes

    Nîmes, 30029 Cedex 9
    France

    Site Not Available

  • Universitätsklinikum Aachen

    Aachen, Nordrhein-Westfalen 52074
    Germany

    Site Not Available

  • Universitätsklinikum Jena

    Jena, Thuringen 07747
    Germany

    Active - Recruiting

  • Universitätsmedizin Mannheim

    Mannheim, Baden-Wuerttemberg 68167
    Germany

    Site Not Available

  • A.O. San Gerardo di Monza - L'Ospedale San Gerardo di Monza e l'Università di Milano

    Monza, Lombardia 20900
    Italy

    Active - Recruiting

  • Clinical Research Center Spółka z Ograniczoną Odpowiedzialnością Medic-R sp. k.

    Poznań, 60-848
    Poland

    Site Not Available

  • Dolnośląskie Centrum Transplantacji Komórkowych z Krajowym Bankiem Dawców Szpiku

    Wrocław, Dolnoslaskie 53-439
    Poland

    Active - Recruiting

  • Oncomed

    Timişoara, 300329
    Romania

    Active - Recruiting

  • Hospital Universitario de Gran Canaria Doctor Negrin

    Las Palmas De Gran Canaria, Las Palmas 35010
    Spain

    Active - Recruiting

  • National Taiwan University Hospital

    Taipei City, Taipei 100
    Taiwan

    Active - Recruiting

  • Hospital Privado - Centro Medico de Cordoba - Oncology

    Córdoba, X5016KEH
    Argentina

    Active - Recruiting

  • Fakultní Nemocnice Královské Vinohrady

    Prague, 10034
    Czechia

    Site Not Available

  • University General Hospital of Ioannina

    Ioánnina, Ioannina 45500
    Greece

    Active - Recruiting

  • Szabolcs-Szatmár-Bereg Megyei Kórházak és Egyetemi Oktatókórház

    Nyíregyháza, Szabolcs-Szatmar-Bereg 4400
    Hungary

    Active - Recruiting

  • ASST Grande Ospedale Metropolitano Niguarda

    Milano, 20162
    Italy

    Active - Recruiting

  • Policlinico Universitario Agostino Gemelli

    Roma, 00168
    Italy

    Active - Recruiting

  • CHA Bundang Medical Center, CHA University

    Seongnam-si, Seongnam-si
    Korea, Republic of

    Active - Recruiting

  • Hospital San Pedro de Alcantara

    Cáceres, 1003
    Spain

    Active - Recruiting

  • Hospital Universitario Virgen de la Victoria

    Málaga, 29010
    Spain

    Active - Recruiting

  • Hospital Universitario Son Espases

    Palma de Mallorca, 07120
    Spain

    Active - Recruiting

  • Chang Gung Medical Foundation - ChiaYi Chang Gung Memorial Hospital - Chiayi Branch

    Chiayi City,
    Taiwan

    Active - Recruiting

  • Monash Medical Centre

    Clayton, Victoria 3168
    Australia

    Active - Recruiting

  • FN Hradec Kralove

    Králová, 500 05
    Czechia

    Active - Recruiting

  • Fakultní Nemocnice Olomouc

    Olomouc, 779 00
    Czechia

    Site Not Available

  • Universitaetsklinikum Essen

    Essen, Nordrhein-Westfalen 45147
    Germany

    Active - Recruiting

  • Assuta MC

    Tel Aviv, 64239
    Israel

    Active - Recruiting

  • AOU Careggi

    Firenze, 50141
    Italy

    Active - Recruiting

  • Ospedale Maggiore Policlinico, Fondazione IRCCS Ca' Granda

    Milano, 20122
    Italy

    Active - Recruiting

  • Spitalul Clinic Coltea

    Bucuresti, 030171
    Romania

    Active - Recruiting

  • Institutul Regional de Oncologie Iasi

    Iaşi, 700483
    Romania

    Active - Recruiting

  • Saint-Petersburg SMU I.P.Pavlov

    St Petersburg, 197089
    Russian Federation

    Site Not Available

  • Hospital Universitari Germans Trias i Pujol

    Badalona, Barcelona 08916
    Spain

    Active - Recruiting

  • The Kirklin Clinic of UAB Hospital

    Birmingham, Alabama 35294
    United States

    Site Not Available

  • Centro Medico San Luis

    Caba, 1425
    Argentina

    Active - Recruiting

  • Fiona Stanley Hosital

    Murdoch, Western Australia 6150
    Australia

    Active - Recruiting

  • South Eastern Private Hospital

    Noble Park, 3174
    Australia

    Active - Recruiting

  • Instituto COI São Paulo

    São Paulo, 1321001
    Brazil

    Active - Recruiting

  • Praxis für Hämatologie und Onkologie

    Saarbrücken, 66113
    Germany

    Active - Recruiting

  • Prince of Wales Hospital - Medicine

    Shatin,
    Hong Kong

    Active - Recruiting

  • Somogy Megyei Kaposi Mór Oktató Kórház

    Kaposvár, Somogy 7400
    Hungary

    Site Not Available

  • Assaf Harofeh Medical Center - Hematology

    Zerifin, 7030000
    Israel

    Active - Recruiting

  • Medicover

    Bucuresti, 060201
    Romania

    Active - Recruiting

  • Hospital Erasto Gaertner

    Curitiba, Parana 81520
    Brazil

    Active - Recruiting

  • Centro de oncologia Leonardo da Vinci

    Fortaleza, Ceara 60140-025
    Brazil

    Active - Recruiting

  • Vseonecma fakultni nemocrince V Praze

    Nové Město,
    Czechia

    Active - Recruiting

  • Technische Universität Dresden

    Dresden, Sachsen 01307
    Germany

    Active - Recruiting

  • Klinikum Rechts der Isar der Technischen Universität München Apotheke

    München, Bayern 81675
    Germany

    Active - Recruiting

  • University Campus of Patras - Hematology

    Patras, 26504
    Greece

    Active - Recruiting

  • Rabin Medical Center - Beilinson Hospital

    Petah Tikva, 49100
    Israel

    Active - Recruiting

  • Universidad Autonoma de Nuevo Leon (UANL) - Hospital Universitario "Dr. Jose Eleuterio Gonzalez

    Monterrey, Nuevo Leon 64460
    Mexico

    Active - Recruiting

  • Spitalul Clinic Judetean de Urgenta Tg Mures

    Târgu-Mureş, 540136
    Romania

    Active - Recruiting

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