Interest of Eosinopia in the Diagnosis of Infection in the Emergency Department

Last updated: April 29, 2019
Sponsor: University Hospital, Strasbourg, France
Overall Status: Active - Recruiting

Phase

N/A

Condition

White Cell Disorders

Treatment

N/A

Clinical Study ID

NCT03467672
6228
  • Ages > 18
  • All Genders

Study Summary

Several studies have described the interest of eosinopenia as a marker of infection in internal medicine or in intensive care units. Eosinopenia is an inexpensive and easily accessible biological marker of sepsis. Retrospective work in the adult emergency departments of Strasbourg University Hospitals has shown the good specificity of this biological sign for the diagnosis of infection. Our work aims to confirm the results by a more meaningful study.

Main objective: Evaluation of the interest of eosinopenia in the diagnosis of bacterial infection in ED.

Methodology: inclusion of all patients with criteria for bacterial infection in ED, inclusion of an equivalent number of uninfected control patients.

Duration : 12 months Multicentric prospective study 6 centers : Strasbourg, Hôpital Nord Franche comté, Sélestat, Wissembourg, Colmar, Mulhouse

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • major patient

  • patient suspected of infection and benefiting from the routine practice of NFS,whatever the indication during his / her visit to the emergency room.

  • patient with or without criteria for bacterial infection

  • patient affiliated to a social security scheme

  • patient (or legal representative) who has agreed to participate in the study

Exclusion

Exclusion Criteria:

  • anti tumor chemotherapy

  • immunosuppressive treatment

  • corticotherapy

  • antibiotherapy in progress

  • malignant hemopathy

  • evolutionary cancer

  • refusal to participate in the study

  • subjects under safeguard of justice

  • subject under guardianship or curatorship

Study Design

Total Participants: 2000
Study Start date:
March 23, 2018
Estimated Completion Date:
March 31, 2020

Connect with a study center

  • CH de COLMAR

    Colmar, 68024
    France

    Active - Recruiting

  • CH de MULHOUSE

    Mulhouse, 68051
    France

    Active - Recruiting

  • Les Hôpitaux Universitaires de Strasbourg

    Strasbourg, 67098
    France

    Active - Recruiting

  • Ch Selestat

    Sélestat, 67600
    France

    Active - Recruiting

  • CH Nord Franche comte

    Trévenans, 90400
    France

    Active - Recruiting

  • Ch Wissembourg

    Wissembourg, 67166
    France

    Active - Recruiting

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