Home Non Invasive Ventilation for COPD Patients

Last updated: July 19, 2017
Sponsor: University Hospital, Rouen
Overall Status: Active - Recruiting

Phase

N/A

Condition

Lung Injury

Respiratory Failure

Treatment

N/A

Clinical Study ID

NCT03221101
2013-AO1276-39 2010/080/HP
CPP-SC 010/2013
  • Ages 18-85
  • All Genders

Study Summary

Chronic Obstructive Pulmonary Disease (COPD) patients are more likely to develop acute hypercapnic respiratory failure. In the acute phase, non invasive ventilation has been shown to improve mortality and reduce intubation rate. Few studies are available about long term benefits of home non invasive ventilation in COPD patients with chronic hypercapnic respiratory failure who survived after an acute episode. The purpose of this study is to determine whether home non invasive ventilation can reduce recurrent acute hypercapnic respiratory failure in COPD patients who survived an acute hypercapnic respiratory failure episode treated by non invasive ventilation.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • COPD patients who survived after an acute episode of hypercapnic respiratory failure

  • patients weaned from ventilation ( non invasive ventilation or mechanical ventilation)prescribed for acute episode since at least five days with following arterial bloodgas : pH > 7.35 and PCO2 > = 45 mmHg

Exclusion

Exclusion Criteria:

  • severe obstructive sleep apnea ( DI > 30/h)

  • Non COPD cause of respiratory failure

  • Serious comorbidity

  • Adverse psychological status

Study Design

Total Participants: 86
Study Start date:
December 01, 2011
Estimated Completion Date:
December 31, 2025

Connect with a study center

  • CH Dieppe

    Dieppe,
    France

    Active - Recruiting

  • CH Elbeuf

    Elbeuf,
    France

    Active - Recruiting

  • Le Havre, Jacques Monod Hospital

    Montivilliers, 76290
    France

    Active - Recruiting

  • CHU de Rouen

    Rouen, 76000
    France

    Active - Recruiting

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