Swiss Primary Biliary Cholangitis Cohort Study

Last updated: August 13, 2025
Sponsor: Fondazione Epatocentro Ticino
Overall Status: Active - Recruiting

Phase

N/A

Condition

Liver Disorders

Hyponatremia

Gall Bladder Disorders

Treatment

N/A

Clinical Study ID

NCT03146910
SASL39 - Swiss PBC Cohort
  • Ages > 18
  • All Genders

Study Summary

Research project in which biological material is sampled and health-related medical data is collected. In addition, already existing health-related medical data are used for further research. Coded data are used.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • diagnose of Primary biliary cholangitis (according to EASL Clinical PracticeGuidelines: management of cholestatic liver diseases).

  • Subjects with isolated anti-mitochondrial antibodies and/or isolated PBC-specificanti-nuclear antibodies are also included

  • Patients/subjects aged at least 18 years and living in Switzerland are included

Exclusion

Exclusion Criteria:

  • N/A

Study Design

Total Participants: 500
Study Start date:
February 15, 2017
Estimated Completion Date:
December 31, 2030

Study Description

Enrolment visit and one follow-up visit at least once a year are planned.

Whole blood is collected for biobanking once a year. Optionally, if available and collected during normal clinical procedures, liver fragments are obtained.

To collect high quality prospective data on a rare disease in order to elucidate epidemiology, natural history, response to treatment and outcome. In addition, the biobank allows addressing specific scientific issues on a variety of open questions. The cohort will provide a platform for carrying out scientific research projects on PBC. In addition, the cohort will allow collaboration with reference networks on PBC abroad.

Connect with a study center

  • Fondazione Epatocentro Ticino

    Lugano, Ticino 6900
    Switzerland

    Active - Recruiting

  • Gastroenterologie und Hepatologie, Clarunis - Universitäres Bauchzentrum Basel

    Basel, 4031
    Switzerland

    Active - Recruiting

  • Inselspital

    Bern, 3010
    Switzerland

    Active - Recruiting

  • Spital Bülach

    Bülach, 8180
    Switzerland

    Active - Recruiting

  • Kantonsspital Graubünden

    Chur, 7000
    Switzerland

    Active - Recruiting

  • Hôpitaux Universitaires de Genève, Service de Gastroentérologie & Hépatologie, Département des Spécialités

    Geneve, 1205
    Switzerland

    Active - Recruiting

  • CHUV: Centre hospitalier universitaire vaudois

    Lausanne, 1005
    Switzerland

    Active - Recruiting

  • Kantonsspital Baselland

    Liestal, 4410
    Switzerland

    Active - Recruiting

  • EOC Ospedale Regionale di Lugano - Italiano

    Lugano, 6900
    Switzerland

    Active - Recruiting

  • Luzerner Kantonsspital

    Luzern, 6000
    Switzerland

    Active - Recruiting

  • Kantonsspital St.Gallen

    Sankt Gallen, 9007
    Switzerland

    Active - Recruiting

  • Kantonsspital Winterthur

    Winterthur, 8400
    Switzerland

    Active - Recruiting

  • Universitätsspital Zürich

    Zurich, 8091
    Switzerland

    Active - Recruiting

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