Molecular Hydrogen for Cognitive Function and Performance in Elderly

Last updated: October 27, 2016
Sponsor: University of Novi Sad, Faculty of Sport and Physical Education
Overall Status: Completed

Phase

3

Condition

Dementia

Memory Loss

Memory Problems

Treatment

N/A

Clinical Study ID

NCT02830854
DK-DR16-02
  • Ages > 65
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

A variety of non-pharmacological interventions have been used in the management of Alzheimer's disease (AD) and similar cognitive disorders in elderly, yet no therapeutic modality has demonstrated conclusive positive results in terms of effectiveness. Although it is still unknown what triggers AD, recent studies have shown that AD is associated with brain energy depletion, oxidative stress, and mitochondrial dysfunction. Since supplemental molecular hydrogen (H2) supports cell energy production and acts as a highly bioavailable mitochondria-related antioxidant, it may provide an ideal agent to facilitate treatment and perhaps prevention of AD and similar cognitive disorders in elderly. The overall hypothesis to be evaluated in this project is that administration of H2 will positively affect patient-reported outcomes and clinical biomarkers in men and women suffering from AD.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age over 65

  • No psychiatric comorbidities

Exclusion

Exclusion Criteria:

  • Use of dietary supplements 4 weeks before study commence

Study Design

Total Participants: 13
Study Start date:
July 01, 2016
Estimated Completion Date:
September 30, 2016

Connect with a study center

  • Applied Bioenergetics Lab at Faculty of Sport and PE

    Novi Sad, Vojvodina 21000
    Serbia

    Site Not Available

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