Last updated: March 29, 2024
Sponsor: University of Colorado, Denver
Overall Status: Active - Recruiting
Phase
N/A
Condition
Down's Syndrome
Mild Cognitive Impairment
Dementia
Treatment
N/AClinical Study ID
NCT02612376
15-1774
Ages > 18 All Genders Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
- Persons with age-related MCI or AD according to clinical diagnosis, consistent withNIA-AA diagnostic criteria
- Community-dwelling controls, Age > 60 years
- Ability to complete baseline assessments
- Has an informant (study partner) available to complete functional interviews/surveymeasures annually
Exclusion
Exclusion Criteria:
- Presence of concomitant medical, neurological, or psychiatric illness or conditionthat in the opinion of the investigators would confound interpretation of studyresults. These include: Korsakoff encephalopathy; active substance abuse; hepatitis C;opportunistic brain infection; brain tumor; active neoplastic disease (skin tumorsother than melanoma are not exclusionary; participants with stable prostate cancer maybe included at the discretion of the project director); multiple sclerosis; history ofclinically significant stroke; current evidence or history in the past 2 years offocal brain lesion, head injury with loss of consciousness, or DSM-V criteria for anymajor psychiatric disorder, including psychosis, major depression, bipolar disorder,alcohol or substance abuse; blindness, deafness or any other disability which mayprevent the participant from participating or cooperating in the protocol.
- Presence of contraindication for MRI scan
Study Design
Total Participants: 800
Study Start date:
February 01, 2016
Estimated Completion Date:
January 31, 2025
Connect with a study center
University of Colorado, Denver
Aurora, Colorado 80045
United StatesActive - Recruiting
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