Specimen Collection from Patients with Non-Hematologic Cancer for Use in Development of a Liquid Biopsy Assay

Inclusion Criteria:

• Subject is 18 years of age or older;

• Subject is willing to provide written informed consent;

• Subject has a diagnosis of a non-hematologic cancer, has tumor in the body, and haseither;

1. residual tumor tissue available for testing by the Sponsor; or

2. genomic profiling results from an IVD or LDT assay performed on tumor biopsytissue; or

3. an invasive procedure (biopsy, surgery) scheduled following the Baseline Visitfrom which residual tumor tissue can be available for testing by the Sponsor.

• Subject is able, in the professional opinion of the investigator, to provide wholeblood at the Baseline Visit and at the Interim Visits.

Exclusion Criteria:

• Underwent curative-intent surgery for management of the presently diagnosed tumor,at any time prior to the Baseline Visit.

• Underwent targeted or non-targeted chemotherapy, hormone receptor blocking therapy,or radiation therapy prior to the Baseline Visit.

• Underwent an invasive procedure (biopsy, surgery, thermal ablation) in the 7 daysprior to any blood collection (baseline or follow-up).

• Any medical or mental condition that would interfere with the subjects' ability towillingly give written informed consent.