Transcranial Direct Current Stimulation (tDCS) as an add-on Therapy for Treatment of Major Depressive Disorder. (DEPTDCS2014)

Last updated: September 11, 2018
Sponsor: Turku University Hospital
Overall Status: Active - Recruiting

Phase

2/3

Condition

Depression

Treatment

N/A

Clinical Study ID

NCT02521883
T248/2014
  • Ages 18-70
  • All Genders

Study Summary

The aim is to investigate the safety and effectiveness of transcranial Direct Current Stimulation (tDCS) in patients with moderate to severe major depression compared to patients treated with conventional therapy. The tDCS will be used as add-on to conventional therapy.

This is a randomized 2-arm parallel, double blind study comparing 2 groups of 60 patients.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Fulfils the ICD-10 diagnostic criteria for moderate or severe major depressive episode (F32), or recurrent major depressive episode (F33)

  • Able to understand the purpose and potential risks of the study

  • Able to sign informed consent

Exclusion

Exclusion Criteria:

  • intracranial metal implants or other foreign intracranial metal object

  • history of neurological conditions e.g. epilepsy, stroke (ischemic or haemorrhagic);brain tumor; increased intracranial pressure etc.

  • schizophrenia

  • bipolar disorder

  • psychotic disorder

  • substance abuse or dependency

  • contra-indications to tDCS

  • personality disorder that may prevent him/her to commit to the study

  • skin lesion in the area of stimulation

  • planned treatment of current depressive episode with ECT or rTMS

Study Design

Total Participants: 120
Study Start date:
March 01, 2015
Estimated Completion Date:
March 31, 2020

Connect with a study center

  • PHSOTEY, Psykiatrian tulosalue, ECT-yksikkö

    Lahti, 15850
    Finland

    Active - Recruiting

  • VSSHP Psykiatria, Liedon aikuispsykiatrian poliklinikka

    Lieto, 21420
    Finland

    Active - Recruiting

  • Tampere University Hospital, Pitkäniemen sairaala

    Tampere, 33380
    Finland

    Site Not Available

  • Turku University Hospital

    Turku, 20521
    Finland

    Active - Recruiting

  • Sektionen för affektiva sjukdomar, Norra Stockholms Psykiatri, Stockholms läns sjukvårdsområde

    Stockholm, Stockholms Län 10233
    Sweden

    Active - Recruiting

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