Serum Parameter Prior and After EUS-guided Fine Needle Aspiration of the Pancreas

Last updated: February 10, 2019
Sponsor: Helios Albert-Schweitzer-Klinik Northeim
Overall Status: Active - Recruiting

Phase

N/A

Condition

Pancreatitis

Treatment

N/A

Clinical Study ID

NCT02397993
Helios 6/1/15
  • Ages > 18
  • All Genders

Study Summary

Endoscopic ultrasonography (EUS ) -guided fine needle aspiration (EUS -FNA ) of focal pancreatic lesions is an essential diagnostic procedure with high therapeutic effect in clinical routine.

The aim of this study is to determine the levels of serum lipase, serum amylase and the tumor marker CA 19-9 prior and after EUS-FNA. In animal experiments on dogs, an increase of all three parameters was observed after surgery on the pancreas. For humans, these clinically important data are not yet available .

It is assumed that the probability of pancreatitis with increased activity of lipase and amylase will rise with the number of puncture procedures as well as the size of the puncture needle. In addition, the post-interventional assessment of the tumor marker CA 19-9 could result in a false positive assumption of malignant neoplastic pancreatic lesion.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • independent indication for pancreatic EUS-FNA

  • age ≥ 18 years

  • patient able to give informed consent

Exclusion

Exclusion Criteria:

  • Contraindications for EUS-FNA

  • pregnancy

  • no informed consent available

  • known stenosis of esophagus or duodenum

  • relevant coagulation disorders

Study Design

Total Participants: 208
Study Start date:
March 01, 2015
Estimated Completion Date:
December 31, 2020

Connect with a study center

  • Department of Gastroenterology, University Medical Center

    Göttingen, Lower Saxony 37075
    Germany

    Active - Recruiting

  • HELIOS Albert-Schweitzer Hospital Northeim

    Northeim, Lower Saxony 37154
    Germany

    Active - Recruiting

  • Department of Gastroenterology, Klinikum Bielefeld

    Bielefeld, North-Rhine Westphalia 33604
    Germany

    Active - Recruiting

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