Triple Negative Breast Cancer and Germline Hereditary Breast and Ovarian Cancer Mutation Carrier Registry

Inclusion criteria include:

Triple Negative Breast Cancer

• ER/PR <10% and HER negative per current ASCO/CAP guidelines

• Stages I-IV

• Any age at diagnosis

• Patient must be within 5 years of diagnosis

• Eligible regardless of genetic testing status

• Genetic testing recommended for patients meeting NCCN and Medicare guidelines

AND/OR

Germline mutation Carriers

• Patients with deleterious or uncertain mutations in HBOC genes (BRCA, PTEN, P53, -PALB2 etc) are eligible regardless of type/site of cancer

• Healthy patients harboring mutations also eligible

• There is no time limit from the time of diagnosis of cancer and enrollment.

• Eligible regardless of personal history of cancer

Exclusion Criteria include:

Triple Negative Breast Cancer -Patient is not within five years of diagnosis

Germline mutation Carriers:

-Patient only carries a HBOC mutation that is classified as "polymorphism" of "favor polymorphism"