Detection of Tumor DNA in Blood Samples From Cancer Patients

Last updated: August 12, 2019
Sponsor: Lexent Bio, Inc.
Overall Status: Active - Recruiting

Phase

N/A

Condition

Neoplasms

Cancer

Treatment

N/A

Clinical Study ID

NCT02288754
LB1985106
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The aim of this study is to employ genomic detection methodologies to measure the relative amount of tumor nucleic acids in the blood of a cancer patient with diagnosed metastatic disease that is either commencing, currently undergoing or completed cytotoxic chemotherapy treatment. More generally, this approach will allow us to develop a quantitative measure of therapy efficacy via the counting of the relative changes in tumor molecules over the course of treatment.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age 18 years or older

  • Have metastatic disease with from a solid tumor (e.g. breast, lung, colon, pancreas,ovary, prostate...) or stage II or III solid tumors undergoing curative surgery orneoadjuvant therapy followed by surgery

  • Starting treatment or a new line of treatment

  • Able to understand and grant informed consent

  • Able to have their blood drawn

Exclusion

Exclusion Criteria:

  • Unable to grant informed consent or comply with all study procedures.

  • Has a hematological malignancy, i.e. myeloma, lymphoma, MDS, leukemia

Study Design

Total Participants: 500
Study Start date:
December 01, 2014
Estimated Completion Date:
November 30, 2020

Connect with a study center

  • James Sinclair, MD

    La Jolla, California 92037
    United States

    Site Not Available

  • Sharp Clinical Oncology Research

    San Diego, California 92123
    United States

    Site Not Available

  • Cancer Care Associates

    Torrance, California 90277
    United States

    Active - Recruiting

  • Summit Cancer Center

    Post Falls, Idaho 83854
    United States

    Site Not Available

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