Effect of Gabapentin on Pain of the Second Cataract Surgery

Last updated: May 10, 2015
Sponsor: Seoul National University Hospital
Overall Status: Trial Status Unknown

Phase

4

Condition

Eye Disease

Eye Disorders/infections

Vision Loss

Treatment

N/A

Clinical Study ID

NCT02127853
SerialCataractGaba
  • Ages 20-80
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Gabapentin pretreatment may reduce hyperalgesia occurring at the second surgery in serial, bilateral cataract surgery.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patient of ASA(American Cociety of Anesthesiology) class I, II, III between age 20 to 80, scheduled for serial bilateral cataract surgery(1 weel interval)

Exclusion

Exclusion Criteria:

  • refuse to participate

  • BMI<16 or BMI >30

  • severe cardiovascular, pulmonary, renal disease

  • alcohol or drug abuse

  • currently taking CNS(central nervous system) inhibitory drugs

  • taking antiacids

  • depressive disorder pregnancy

Study Design

Total Participants: 70
Study Start date:
July 01, 2014
Estimated Completion Date:
February 29, 2016

Study Description

Hyperalgesia occurring at the second operation in bilateral eye surgery is well known, and mechanism of central sensitization might be involved. Gabapentin is known to lower the effect of central sensitization, and its effect on acute postoperative pain has been reported. Therefore, pretreatment of gabapentin after first operation may reduce the pain at second operation.

Connect with a study center

  • Seoul National University Hospital

    Seoul, 110-799
    Korea, Republic of

    Active - Recruiting

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