China PEACE-Prospective PCI Study

Last updated: August 27, 2015
Sponsor: China National Center for Cardiovascular Diseases
Overall Status: Completed

Phase

N/A

Condition

Cardiac Disease

Chest Pain

Coronary Artery Disease

Treatment

N/A

Clinical Study ID

NCT01624922
WSGY-201202025-4
  • Ages > 18
  • All Genders

Study Summary

Coronary heart disease (CHD) pose a serious health threaten to population. PCI, as a well-proved and booming measure in CHD management, is invasive and of high cost, however the knowledge about the real-life PCI use in China is limited. By consecutively recruiting PCI patients in 30 geographically representative highest-rank hospitals, this study will examine various real-life factors, that may affect patients recovery after the procedure. Practical guidelines, appropriateness criteria and quality evaluative system for PCI will be established based on the findings, to improve patients outcomes in future finally.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Hospitalized patients undergoing a percutaneous coronary intervention (PCI) withstents implantation for coronary lesions.

Exclusion

Exclusion Criteria:

  • Previously enrolled in the PEACE study

Study Design

Total Participants: 5185
Study Start date:
December 01, 2012
Estimated Completion Date:
July 31, 2015

Study Description

Cardiovascular disease (CVD) is a major concern in public health globally, as well as in China, and remarkable variations of resources available and health system performance have been noted. Relatively limited information is available about how evidence-based therapies are incorporated appropriately into routine clinical practice. In addition, little information is available about the magnitude and quality of PCI, which has developed rapidly during the past several decades. Practical and applied knowledge from large unselected population is needed to guide practice and policy for quality improvement and cost reduction.

This study will enroll patients undergoing PCI after admission consecutively in 30 tertiary hospitals scattered all over China. At study entry, participants will be interviewed during their index hospitalization, to collect information about symptoms, functioning, quality of life, and medical care. Demographic characteristics, medical history, clinical features, diagnostic tests, medications, procedures, and in-hospital outcomes of patients will be abstracted from medical records by well trained professional abstractors. And CAG imaging will be reviewed by national and international expert panels. At 1 month, 6 month, and 12 month after discharge, participants will return to the clinic for follow up visits, a face-to-face interview will be conducted to get information about clinical events, symptoms, functioning, quality of life, and medical care during the recovery period. At 1-Month and 12-Month follow-up visit, blood and urine sample will be collected. Participants' blood samples will be stored for future biologic and genetic studies. This study will examine various real-life factors that may affect patients recovery after PCI, including patients' characteristics and treatment measures. Practical guidelines, quality evaluative system, and appropriateness criteria will be established based on the findings, to improve patients outcomes in future finally.

Connect with a study center

  • Fuwai Hospital

    Beijing, Beijing 100037
    China

    Site Not Available

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