Last updated on September 2018

Study of Perampanel as Adjunctive Treatment for Inadequately Controlled Seizures Associated With Lennox-Gastaut Syndrome


Brief description of study

This study is being conducted to demonstrate that perampanel given as adjunctive anti-epileptic treatment is superior to placebo in reducing the number of drop seizures in participants with inadequately controlled seizures associated with Lennox-Gastaut Syndrome (LGS).

Detailed Study Description

This is a multicenter, double-blind, randomized, placebo-controlled, parallel-group study of perampanel as adjunctive therapy in participants with inadequately controlled seizures associated with LGS. The study will consist of 3 phases: Prerandomization (4 to 8 weeks), Randomization (22 weeks), and Extension (56 weeks).

Clinical Study Identifier: NCT02834793

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Banner - University Medical Center Phoenix
Phoenix, AZ United States
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University of Arkansas for Medical Sciences
Little Rock, AR United States
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Stanford University
Palo Alto, CA United States
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Axcess Medical Research
Loxahatchee Groves, FL United States
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Pediatric Neurology PA
Orlando, FL United States
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University of South Florida
Tampa, FL United States
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Meridian Clinical Research
Savannah, GA United States
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Consultants In Epilepsy and Neurology PLLC
Boise, ID United States
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Rush University Medical Center
Chicago, IL United States
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Mcfarland Clinic PC
Ames, IA United States
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Bluegrass Epilepsy Research LLC
Lexington, KY United States
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University of Kentucky
Lexington, KY United States
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Ochsner Health System
New Orleans, LA United States
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Children's Hospital of Michigan
Detroit, MI United States
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Wayne State University
Detroit, MI United States
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Minnesota Epilepsy Group PA
Saint Paul, MN United States
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Children's Mercy Hospital
Kansas City, MO United States
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Comprehensive Epilepsy Care Center For Children and Adults PC
Saint Louis, MO United States
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St Barnabas Institute of Neurology
Livingston, NJ United States
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Wake Forest Baptist Medical Center
Winston-Salem, NC United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, OH United States
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Cleveland Clinic
Cleveland, OH United States
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Thomas Jefferson University
Philadelphia, PA United States
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Road Runner Research Ltd
San Antonio, TX United States
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Baylor Scott and White Research Institute
Temple, TX United States
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Sentara Medical Group
Norfolk, VA United States
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Rainier Clinical Research Center Inc
Renton, WA United States
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MultiCare Institute for Research and Innovation
Tacoma, WA United States
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University of Wisconsin Hospital and Clinics
Madison, WI United States
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Columbia Saint Mary's
Milwaukee, WI United States
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Medical College of Wisconsin
Wauwatosa, WI United States
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Colorado Children's Hospital
Aurora, CO United States
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Yale University
New Haven, CT United States
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Northwest Florida Clinical Research Group, LLC
Gulf Breeze, FL United States
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NW FL Clinical Research Group, LLC
Gulf Breeze, FL United States
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Pediatric Neurologists of Palm Beach
Loxahatchee Groves, FL United States
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Carle Foundation Hospital
Urbana, IL United States
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Louisiana State University Health Sciences Center
Shreveport, LA United States
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Akron Children's Hospital
Akron, OH United States
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Recruitment Status: Open


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