Last updated on June 2016

Thorough ECG (Electrocardiogram) and Drug Interaction Study With Anetumab Ravtansine and Itraconazole


Brief description of study

Characterize the safety, tolerability, ECG effects, pharmacokinetics and immunogenicity of anetumab ravtansine given as single agent and after inhibition of CYP3A4 and P-gp by concomitant administration of itraconazole in subjects with mesothelin-expressing advanced solid cancers

Clinical Study Identifier: NCT02824042

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UCLA-Santa Monica Medical Center
Santa Monica, CA United States
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Ochsner Medical Center - New Orleans
New Orleans, LA United States
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Henry Ford Health System
Detroit, MI United States
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Washington University School of Medicine
Saint Louis, MO United States
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Dartmouth Hitchock Medical Center
Lebanon, NH United States
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University Hospitals Cleveland Medical Center
Cleveland, OH United States
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Mary Crowley Medical Research Center
Dallas, TX United States
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Blacktown Cancer & Haematology Centre
Blacktown, Australia
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Epworth HealthCare
Richmond, Australia
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CU Saint-Luc/UZ St-Luc
Bruxelles - Brussel, Belgium
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UZ Leuven Gasthuisberg
Leuven, Belgium
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H pital Henri Mondor - Cr teil
Creteil, France
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Centre Georges Francois Leclerc Dijon
Dijon, France
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H pital de la Timone - Marseille
Marseille, France
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Nederlands Kanker Instituut
Amsterdam, Netherlands
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Academisch Ziekenhuis Vrije Universiteit
Amsterdam, Netherlands
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Universitair Medisch Centrum St. Radboud
Nijmegen, Netherlands
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Ciutat Sanit ria i Universitaria de la Vall d'Hebron
Barcelona, Spain
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Fundacion Jimenez Diaz (Clinica de la Concepcion)
Madrid, Spain
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Hospital Virgen de la Victoria
Málaga, Spain
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University College Hospital
London, United Kingdom
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Recruitment Status: Open


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