Last updated on March 2019

A Study to Evaluate the Safety and Efficacy of Upadacitinib (ABT-494) for Induction and Maintenance Therapy in Subjects With Moderately to Severely Active Ulcerative Colitis (UC)


Brief description of study

This study comprises three sub-studies. The objective of sub-study 1 is to characterize the dose-response, efficacy, and safety of upadacitinib compared to placebo in inducing clinical remission in order to identify the induction dose of upadacitinib for further evaluation in sub-study 2. The objective of sub-study 2 is to evaluate the efficacy and safety of upadacitinib compared to placebo in inducing clinical remission in participants. The objective of sub-study 3 is to evaluate the efficacy and safety of upadacitinib compared to placebo in achieving clinical remission in participants who had a response following induction with upadacitinib.

Clinical Study Identifier: NCT02819635

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ABBVIE CALL CENTER

Ieda Hospital /ID# 157781
Toyota-shi, Japan
5.07miles
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ABBVIE CALL CENTER

Aichi Medical University Hosp /ID# 151993
Nagakute, Japan
9.73miles
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Recruitment Status: Open


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