A Phase Ia/Ib Open-Label, Dose-Escalation Study of the Safety and Pharmacokinetics of Tiragolumab as a Single Agent and in Combination With Atezolizumab and/or Other Anti-Cancer Therapies in Patients With Locally Advanced or Metastatic Tumors
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- STATUS
- Recruiting
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- End date
- Oct 5, 2024
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- participants needed
- 660
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- sponsor
- Genentech, Inc.
Summary
This first-in-human open-label, multicenter, dose-escalation and expansion study is designed to evaluate the safety, tolerability, and PK of tiragolumab alone or in combination with atezolizumab and/or other anti-cancer therapies in participants with locally advanced, recurrent, or metastatic incurable tumors for whom standard therapy does not exist, has proven to be ineffective or intolerable, or is considered inappropriate, or for whom a clinical trial of an investigational agent is a recognized standard of care.
Details
| Condition | Advanced/Metastatic Tumors |
|---|---|
| Treatment | Capecitabine, cisplatin, etoposide, carboplatin, Paclitaxel, bevacizumab, Pembrolizumab, Pemetrexed, Atezolizumab, MTIG7192A, Tiragolumab |
| Clinical Study Identifier | NCT02794571 |
| Sponsor | Genentech, Inc. |
| Last Modified on | 22 October 2022 |
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